596. Etiology and Clinical Manifestation of Acute Gastroenteritis in Children of Central Province Area, Korea
Session: Poster Session: Pediatrics I
Friday, October 13, 2006: 12:00 AM
Room: Hall E
Background: The purpose of this study is to evaluate etiology of pathogens and compare them with the clinical course in pediatric patients with symptoms of acute gastroenteritis in central area of Korea.
Methods: Subjects were selected from patients presenting with symptoms of acute gastroenteritis who visited the out patient clinics or admitted to Dankook University Hospital from Dec. 2004 to Sep. 2005. Stool exams that RT-PCR was used to test for norovirus, EIA for rotavirus, adenovirus and astrovirus. Ten species of bacteria(Salmonella spp., Shigella spp., C. perfrigens, Campylobacter spp., E. coli, Vibrio spp., S. aureus, B. cereus, Yersinia spp., and Listeria monocytogenes) were each selectively cultivated and EIA for antigens of C.parvum, E. histolytica and G. lamblia.
Results: A total of 159 subjects were selected and of these 76 cases(47.7%) showed positive. Age distribution showed 5 cases(6.5%) less than one month, 21(19%) from 1-12 months, and 40(33.3%) from 12-48 months. Viruses showed the greatest proportion with 60 subjects(78.9%), rotavirus being the most common reported in 44 cases(73.3%). Bacteria followed with 20 cases(26.3%), nontyphoidal Salmonella in 9 cases, toxin producing S. aureus in 7 cases. Protozoa followed with 21 cases(27.6%), C. parvum in 11 cases and G. lamblia in 10 cases. Infection with more than two organisms was seen in 21 cases(27.6%). High CRP and bloody stool were noted in cases of bacterial infection.
Conclusion: Although rotavirus is the most common cause, it can not be distinguished from other pathogens by clinical symptoms alone. In Salmonella infection, bloody stool is common and CRP is higher than other infection. Protozoa infections and mixed infections are more common than expected. Further study is needed to distinguish the clinical symptoms related to the different types of acute gastroenteritis.
Eun Hee Chung, Assistant Professor1, Ik-Jae IM, Resident2, Kwisung Park, Researcher3, Nak Soo Song, Researcher3, Yun Tae Cha, Researcher4 and  E. Chung, None; I. Im, None; K. Park, None; N. Song, None; Y. Cha, None., (1)Dankook Univ. Hospital, Dep of Pediatrics, Cheoanan, Korea, Republic of, (2)Dankook Univ. Hospital, Dep of Pediatrics, Cheonan, Korea, Republic of, (3)Chungcheongnam-do Health and Environment Research Institute, Daejeon, Korea, Republic of, (4)Chungcheongnam-do Health and Environment Research Institute, Daejeon,, Korea, Republic of


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