25129. Optimal Assay Programs for Donor Screening
Session: Workshop: Optimizing Screening of Organs for Transplantation: New Technologies and Future Directions
Friday, October 24, 2008: 12:00 AM
Room: Mtg Rm 16 (Renaissance)
Susan Stramer, PhD, Scientific Support Office, American Red Cross, Gaithersburg, MD and  S. L. Stramer, None.

Susan Stramer received her BS and MS degrees in Biology and Chemistry from Northern Illinois University where her research interest was water microbiology. She received her Ph.D. from the University of Wisconsin-Madison in Bacteriology with a minor in Toxicology in 1984. Her research focused on poliovirus survival in water and wastewater as a model system for water-borne enteric viruses. She then spent 4 years as a postdoctoral fellow at the U.S. Centers for Disease Control and Prevention at the Hepatitis Branch in Phoenix AZ and then in Atlanta GA working with novel culture and quantitative methods, and molecular characterization of various isolates of hepatitis A virus. Following that, she was employed at Abbott Laboratories in their Diagnostic Division for nine years working in the areas of product development, R/D and scientific affairs in support of hepatitis and retroviral assays. During her time at Abbott, she managed most of the blood donor screening assay manufacture, support and product development. In 1995, she joined the American Red Cross as Laboratory Director for the National Confirmatory Testing Laboratory. She now serves as the Executive Scientific Officer at the Scientific Support Office within Biomedical Services’ Medical Office where she provides scientific leadership in the area of infectious diseases for the National Testing Laboratories and blood collection regions of the Red Cross. Dr. Stramer has published over 100 papers and has been a representative on numerous committees of the AABB and the ISBT including serving on the AABB Board of Directors for the Mid-Atlantic district (2004-2008), as Secretary Treasurer (2009-2010) and now as the President-Elect. She is also a liaison to the Transfusion Medicine Committee of the College of American Pathologists and a member of the Scientific Advisory Committee of HemaQuebec. Along with collaborators, Dr. Stramer was a recipient of the Charles C Shepard Science award from the CDC in 1999 and was nominated for the same award in 2004 and 2009. She has also won the American Red Cross Tiffany Award for Employee Excellence in 2002 and the Spirit of Excellence Award in 2003. She was also honored in 2010 as the recipient of the Perkins Award and Lectureship in recognition of her contributions to the understanding of transfusion-transmitted infectious diseases, and the implementation of evidence-based measures to reduce their risk and assess their impact. Karafin MS, Stramer S.L. The scientific method at work: xenotropic murine leukemia virus-related virus is neither a cause of chronic fatigue syndrome nor a threat to the blood supply. Transfusion 2012;52:222-5. Dodd RY, Hackett JR Jr., Linnen JM, Dorsey K, Wu Y, Zou S, Qiu X, Swanson PA, Schochetman G, Gao K, Carrick JM, Krysztof DE, Stramer SL. Xenotropic murine leukemia virus-related virus does not pose a risk to blood recipient safety. Transfusion 2012;52:298-306. Stramer SL, Zou S, Notari EP, Foster GA, Krysztof DE, Musavi F, Dodd RY. Blood donation screening for hepatitis B virus markers in the era of nucleic acid testing: are all tests of value? Transfusion 2012;52:440-6. Zou S, Stramer SL, Dodd RY. Donor testing and risk: Current prevalence, incidence, and residual risk of transfusion-transmissible agents in US allogeneic donations. Transfusion Medicine Reviews 2012;26:119-28. Delwart E, Slikas E, Stramer SL, Kamel H, Kessler D, Krysztof D, Tobler LH, Carrick DM, Steele W, Todd D, Wright DJ, Kleinman SH, Busch MP, for the NHLBI-REDS-II Study Group. Genetic diversity of recently acquired and prevalent HIV, hepatitis B virus, and hepatitis C virus infections in US blood donors. Journal of Infectious Diseases 2012;205:875-85. Stramer SL, Collins C, Nugent T, Wang X, Fuschino M, Heitman JW, Law J, Krysztof DE, Kiely N, Todd D, Vermeulen NMJ, Harrington K, Kamel H, Kelvin DJ, Busch MP, St. George K, Hewlett IK, Linnen JM, Norris PJ, for the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II). Sensitive detection assays for influenza RNA do not reveal viremia in US blood donors. Journal of Infectious Diseases 2012;205:886-94. Mohammed H, Tomashek KM, Stramer SL, Hunsperger E. Prevalence of anti-dengue immunoglobulin G antibodies among American Red Cross blood donors in Puerto Rico, 2006. Transfusion 2012;doi:10.1111/j.1537-2995.2011.03492.x. Martin LA, Stramer SL, Kuhns MC, Schlauder GG. Correlation of improved hepatitis B surface antigen detection limits with hepatitis B virus DNA nucleic acid test yield in blood donations. Transfusion 2012;doi:10.1111/j.1537-2995.2011.03553.x. Benjamin RJ, Stramer SL, Leiby DA, Dodd RY, Fearon M, Castro E. Trypanosoma cruzi infection in North American and Spain: evidence in support of transfusion transmission. Transfusion 2012; doi:10.1111/j.1537-2995.2011.03554.x. Stramer SL, Linnen JM, Carrick JM, Foster GA, Krysztof DE, Zou S, Dodd RY, Tirado-Marrero LM, Hunsperger E, Santiago GA, Muñoz-Jordán JL, Tomashek KM. Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico. Transfusion 2012;doi:10.1111/j.1537-2995.2012.03566.x. Cantey PT, Stramer SL, Townsend RL, Kamel H, Ofafa K, Todd CW, Currier M, Hand S, Varnado W, Dotson E, Hall C, Jett PL, Montgomery SP. The United States Trypanosoma cruzi Infection Study: evidence for vector-borne transmission of the parasite that causes Chagas disease among United States blood donors. Transfusion 2012;doi:10.1111/j.1537-2995.2012.03581.x.



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