K-4105. Quantifying the Burden of Healthcare-Associated Infections in Hospitals
Session: Poster Session: Infection Control, Isolation Precautions, and Nosocomial Infections and Legionella
Tuesday, October 28, 2008: 12:00 AM
Room: Hall C
Background: Healthcare-associated infections (HAI), which patients acquire while receiving treatment for other conditions, are 1 of the top 10 causes of death in the U.S. Healthcare governing and accrediting bodies are calling for a reduction in HAI cases as a means for improving patient safety and outcomes. Two common HAIs include methicillin-resistant Staphylococcus aureus (MRSA) and antibiotic-associated Clostridium difficile diarrhea (CDAD). The objective of this study is to quantify the burden of MRSA and CDAD HAIs in hospitals to the healthcare system and patients in terms of length of stay, mortality rate, and cost. Methods: A retrospective benchmarking analysis was conducted using available claims data obtained from 82 acute care facilities from November 2005 through November 2007. Healthcare-associated MRSA was identified in billing records with V-code V090 and CDAD was identified as pseudomembranous colitis diagnosis code 00845. The analysis compared the LOS, mortality rate, and cost associated with MRSA and CDAD with those of a control group. The control group consisted of a random sample of admissions correspondent to DRGs found in the measurement group. Results: The available data represented a total of 13,297 patients: 8065 with MRSA, 5020 with CDAD, 212 with MRSA and CDAD, and 259,220 control. Lengths of stay were 10.19, 13.03, 20.22, and 5.90, respectively (p=<0.001 for each vs. control). Mortality rates were 3.55%, 8.45%, 8.96%, and 2.96%, respectively (p=<.01 for each vs. control). Overall cost of the hospital stays were $18.091, $24,154, $21,592, and $6584, respectively (p=<.001for each vs. control). Conclusions: Based on this analysis, HAIs consisting of MRSA and CDAD significantly impact the burden of care to healthcare systems and to patients. This data and methods may be used to compare outcomes from an individual acute care facility and a nationwide benchmark. Appropriate practice policies will assist in reducing the unnecessary burden of HAIs and in fulfilling goals and regulations set forth by governing and accrediting bodies.
Blane Schilling, MD, Aspen Healthcare Metrics, Englewood, CO and  B. Schilling,
bioMerieux Role(s): Speaker's Bureau, Received: Speaker Honorarium.