Slide Session:
225. Human Pharmacodynamics of Effect and Toxicity
Monday, October 27, 2008: 1:30 PM-4:00 PM
Room: Constitution B (Grand Hyatt)

Mini Lecture:  Thomas Lodise, PharmD, Albany College of Pharmacy

Moderator:  John Rotschafer, Pharm D, University of Minnesota


1:30 PM
John Rotschafer, Pharm D

1:30 PM
Mini Lecture
Thomas Lodise, PharmD

1:30 PM
Association of Vancomycin (V) Trough Levels with Nephrotoxicity (NT)
Christopher Graber, MD, MPH

; Matthew Bidwell Goetz, MD

; Tamara Pratummas, PharmD

; Thuong Tran, PharmD

1:30 PM
Association Between High Cefepime (CFP) Plasma Concentrations and Neurotoxicity in Febrile Neutropenic Patients with Mild Renal Dysfunction
Andres Pascual, MD

; Frédéric Lamoth

; Laurent Decosterd

; Oscar Marchetti

; Thierry Buclin

; Thierry Calandra, MD, PhD

1:30 PM
Anti-Infective PK/PD - Impacting the Probability of Successful Phase 3 Clinical Trials
Charles Bonapace, PharmD

; John Lazor, PharmD

; Kimberly Bergman, PharmD

; Sarah Robertson, PharmD

1:30 PM
A Thorough QT Study to Define the ECG Effects of Cethromycin (CER) Using a Clinical and a Supratherapeutic Dose Compared to Placebo and Moxifloxacin (MFX) in Healthy Subjects (CL07-001)
Christine Fredericks

; David Eiznhamer, PhD

; Joel Morganroth

; Marci English

; Michael Flavin, PhD

; Nancy Milanesio

; Nestor Rohowsky

; Z Xu

1:30 PM
Cefepime Exposure and Mortality in Pediatric Patients with Acute Myelogenous Leukemia (AML)
Brian Fisher, DO, MPH

; Kateri Leckerman, MS

; Richard Aplenc, MD, MSCE

; Russell Localio, PhD

; Theoklis Zaoutis, MD, MSCE

1:30 PM
Pharmacokinetics-Pharmacodynamics (PK-PD) of Oritavancin (ORI) Efficacy in Patients with Complicated Skin and Skin Structure Infections (cSSSI)
Alan Forrest, PharmD

; Anuradha Prakhya, BS

; Christopher Rubino, PharmD, BCPS

; Jeffrey Hammel, MS

; Jill McCollam, PharmD

; Paul G. Ambrose, PharmD, FIDSA

; Scott Van Wart, MS

; Sujata Bhavnani, PharmD

; Varsha Iyer, PhD

1:30 PM
Plasmatic Inhibitory Quotient (PIQ) Does Not Predict Outcome in MRSA Bacteremia Treated with Glycopeptides
François Jehl

; Guillaume Camuset

; Nicolas Lefebvre

; Yves Hansmann, MD

; Daniel Christmann, MD

; Emmanuel Forestier

CME Credits:

ACPE Credits: 2.5

ACPE Number: 388-999-08-166-L01-P

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