748. Using a One Health Approach to Identify the Emergence and Mitigate the Spread of Potentially Pandemic Zoonoses
Session: Symposium: One World, One Health, One Medicine
Friday, October 21, 2011: 3:45 PM
Room: 153ABC
In order to predict, respond to, and prevent the emergence of novel infectious diseases, we must identify pathogens at their source. Rapid human population growth and environmental changes have resulted in increased numbers of people living in close contact with animals. The resulting increased contact has altered the ecological balance between pathogens and their human and animal hosts. We have built a One Health team with a SMART (Strategic, Measurable, Adaptive, Responsive, and Targeted) surveillance vision, responsive to the fact that zoonotic pathogens account for the majority of emerging infectious diseases in people and that more than three quarters of these are the result of wildlife-origin pathogens. Our approach employs integrated risk modelling, molecular diagnostics, and intensive field studies to detect novel pathogens with pandemic potential early, giving health professionals the best opportunity to prevent emergence or control epidemics at the source of spill-over.


Jonna Mazet, DVM, MPVM, PhD, Wildlife Health Center, University of California, Davis School of Veterinary Medicine, Davis, CA

Jonna Mazet earned her Doctor of Veterinary Medicine and PhD in epidemiology from University of California Davis (UCD). She serves as the Director of the One Health Institute and Wildlife Health Center in the UCD School of Veterinary Medicine. Professor Mazet assists government agencies and the public with emerging infectious diseases and wildlife conservation issues and manages One Health research programs, such as tuberculosis in Africa, disease conflict in Yellowstone National Park, and pathogen pollution of California coastal waters. She is the PI and Global Director for a global early warning system for zoonotic diseases, PREDICT, that is supported by the United States Agency for International Development’s Emerging Pandemic Threats Program. PREDICT is a multi-institutional, transdisciplinary project that is establishing a global surveillance system for potentially pandemic diseases emerging from wildlife using geospatial modeling, epidemiology, genomics, molecular virology, and targeted field surveillance at hot zoonotic disease transmission interfaces. She leads a network of NGOs and governmental agencies to build capacity within the 24 countries to develop surveillance systems and complete the necessary research and surveillance in an attempt to halt the next pandemic, like influenza, SARS, Ebola, and HIV that have preceded the program.



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