53. Getting to the Brain: Dissemination of Cryptococcus Spores
Session: Symposium: Pathogenesis of Central Nervous System Infection
Thursday, October 20, 2011: 1:30 PM
Room: 253ABC

Christina Hull, PhD, Biomolecular Chemistry/Medical Microbiology & Immunology, University of Wisconsin, School of Medicine and Public Health, Madison, WI

Dr. Christina Hull is an Associate Professor of Biomolecular Chemistry and Medical Microbiology & Immunology at the University of Wisconsin, Madison, School of Medicine and Public Health. She graduated from the University of Utah with a degree in Biology and a focus in Biochemistry and Molecular Biology in 1993. She earned her PhD in Biochemistry at the University of California San Francisco in 2000 based on her discovery of mating in the pathogenic yeast Candida albicans. She carried out her post-doctoral fellowship at Duke University in Durham, NC from 2000-2003 with support from a Damon Runyon Cancer Research Foundation Post-doctoral Fellowship. At Duke she discovered the key regulators of sexual development in the soil fungus Cryptococcus, the leading cause of fungal meningoencephalitis in humans. Since establishing an independent research laboratory at UW, Madison in 2003, she has focused on understanding the basic biology of Cryptococcus sexual development, including how the fungus produces infectious particles (spores) and how those particles disseminate from the host lung. Dr. Hull held a Burroughs Wellcome Career Award in the Biomedical Sciences from 2003-2008 and a March of Dimes Basil O'Connor Starter Scholar Research Award from 2005-2007. Dr. Hull's recent research focuses on using a murine model of infection to understand how Cryptococcus spores associate with alveolar phagocytic cells to escape killing by the host immune system and traffic to the central nervous system.

Findings in the abstracts are embargoed until 12:01 a.m. EST Thursday, Oct. 20 with the exception of research findings presented at IDSA press conferences.