112. What's New in the Science of Implant Infections (Biofilm)?
Session: Symposium: Devices and Infections: Biofilm to Bedside
Friday, October 21, 2011: 8:45 AM
Room: 104ABC
Presentation Summary

The bacteria that cause device-related infections always grow in biofilms, from which variable numbers of planktonic cells may be shed.

Because of this biofilm mode-of-growth device related infections are inherently chronic, but may produce acute episodes when planktonic cells are released.

Biofilm bacteria are resistant to antibiotics, so that the device and its biofilm load must be removed before antibiotics can kill residual organisms and resolve the infection.

Because biofilm bacteria grow poorly (if at all) on culture media, device-related infections are very difficult to detect using routine culture methods.



J. William Costerton, PhD, Montana State University/Center for Biofilm Engineering, Bozeman, MT; Allegheny General Hospital and Allegheny-Singer Research Institute, Pittsburgh, PA

J. William Costerton
Dr. J. William Costerton assumed the Directorship of the Center for Biofilm Engineering in January 1993. From 1995-2001 he held the position of Association Dean for Research of the College of Engineering at Montana State University - Bozeman. He came to Montana State University - Bozeman following twenty-three years at the University of Calgary. He was appointed as an Associate Professor of Biology there in 1970, and became Professor in 1975. In 1980 he was appointed t the AOSTRA Research Chair in Microbiology and to the NSERC Industrial Research Chair in Microbiology in 1990. Prior to his work at Calgary, Dr. Costerton was Assistant Professor of Microbiology at MacDonald College of McGill University (1966-70) and completed a post-doctoral fellowship at Cambridge University (1964-66). From 1960-69 he was Dean of Science at Baring Union College, Punjab India.
Dr. Costerton received his Ph.D. in Bacteriology in 1960 from the University of Western Ontario. His early interest in microbial ecology led him to the study of bacteria attached to surfaces - BIOFILMS. His research since has dealt with biofilms in a broad variety of environments; from mountain streams, to industrial systems, to medical devices implanted in humans. He has over 584 publications to his name is mainly referred journals.
His research has brought honors including 2003-2005 Honorary Professor in the Advanced Wastewater Management Centre at the University of Queensland. The 2003 Charles & Nora L. Wiley Faculty Award for Meritorious Research, MSU-Bozeman. In 2002, Dr. Costerton received an honorary degree of Doctor of Science Honoris Causa, presented by the Senate of the University of Guelph in Guelph, Ontario, Canada. The Excellence in Surface Science Award from the Surfaces in Biomaterials Foundation in 2002. The Marian E. Koshland Seminar Series Lecturer at the University of California in Berkeley in 2002. Also in 2002 Dr. Costerton was added to the Highly Cited List on www.isihighlycited.com - the Institute for Scientific Information (ISI) includes the top 250 preeminent individual researchers in each of 21 subject categories who have demonstrated great influence in their field as measured by citations to their work - the intellectual debt acknowledged by their colleagues. Appointed Fellow of the American Association for the Advancement of Science (AAAS) in 1997, the Isaak Walton Killam Memorial Prize for Scientific Achievement in 1990 and the Sir Frederick Haultain Prize from outstanding achievement in the physical sciences in 1986.



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