502. Pre-exposure Prophylaxis for HIV Infection: Healthcare Providers’ Knowledge, Perception, and Willingness to Adopt Future Implementation in the Southern US
Session: Poster Abstract Session: HIV Testing and Prevention
Friday, October 21, 2011
Room: Poster Hall B1
  • 502_AvnishTRIPATHI.pdf (527.4 kB)
  • Background: Pre-exposure prophylaxis (PrEP) has been proposed as a potential biomedical strategy to reduce risk of HIV transmission. To facilitate future implementation of PrEP in health care settings, it is important to explore providers' knowledge and perception of PrEP.

    Methods: A cross-sectional survey of physician and non-physician providers from STD and family planning clinics in South Carolina (SC) and Mississippi (MS) was conducted, from September 2006-January 2008, to access providers' knowledge, perception and willingness to adoption of PrEP. Multivariable logistic and general linear regression with inverse propensity score treatment weights was used for analyses.

    Results: The response rate was 360 (75%) of the 480 providers surveyed (298/392, 76.02%, SC; 62/88, 70.45%, MS). Median age of providers was 46.9 years and a majority were females, 279 (78%); non-Hispanic white, 277 (78%); non-physicians, 254 (71%); and public health providers, 223 (62%).

    PrEP knowledge score was higher among physicians (P=0.001); non-public health providers (P=0.023); and non-Hispanic white (P=0.034). There were significant differences among the providers regarding attitudes and perceptions about PrEP. For example, agreement that 'PrEP would promote people to abandon safe sex practices' was more likely in non-physicians (OR 4.39; 95% CI 2.01-9.67), non-public health providers (OR 2.55; 95% CI 1.17-5.58), and with more STD/HIV experience (OR 5.13; 95% CI 1.08-24.47); and was less likely with higher PrEP knowledge score (OR 0.21; 95% CI 0.05-0.92) and older age (OR 0.83; 95% CI 0.73-0.94).

    The willingness to prescribe PrEP in future was more likely with higher PrEP knowledge score (OR 14.94; 95% CI 3.21-69.61), older age (OR 1.14; 95% CI 1.01-1.29), and in those who agreed with the statement that 'PrEP would empower women' (OR 2.90; 95% CI 1.28-6.61); and was less likely in other race/ethnicity (OR 0.23; 95% CI 0.07-0.76) and in those who agreed that 'PrEP, if not effective could lead to higher HIV transmission' (OR 0.45; 95% CI 0.27-0.75).

    Conclusion: Health-care providers' knowledge and perception will influence willingness to prescribe PrEP. Educating to improve knowledge and mitigating differences may facilitate effective future implementation of PrEP.

    Subject Category: H. HIV/AIDS and other retroviruses

    Avnish Tripathi, MD, MPH1, Chinelo Ogbuanu, MD, PhD1, Mauda Monger, MPH2, James Gibson, MD, MPH3 and Wayne Duffus, MD, PhD4, (1)Arnold School of Public Health, University of South Carolina, Columbia, SC, (2)Mississippi State Department of Health, Jackson, MS, (3)SC Department of Health & Environmental Control, Columbia, SC, (4)South Carolina Dept. of Health and Environmental Control, Columbia, SC


    A. Tripathi, None

    C. Ogbuanu, None

    M. Monger, None

    J. Gibson, None

    W. Duffus, None

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