1266. An Outbreak of Dengue in Central Nepal, 2010
Session: Poster Abstract Session: Travel/Tropical Medicine and Parasitology
Saturday, October 22, 2011
Room: Poster Hall B1
Handouts
  • Outbreak of Dengue in Nepal_Arun.png (409.6 kB)
  • Background: 

    Dengue Fever used to be considered a rare disease entity in Nepalese context till recent past. The first case of Dengue in Nepal was detected in 2004 and few sporadic cases were reported in different districts in 2006. However, there had been a major outbreak of Dengue Fever in central Nepal recently starting from the September 2010. This study was aimed at describing the clinical, laboratory and Radiological profiles of patients with Dengue Fever during the outbreak in chitwan and adjacent districts of Nepal.

    Methods: 

    A prospective and observational analytical study conducted at Chitwan Medical College, Nepal.

    Results: 

    Out of 1456 patients with acute febrile illness, 426 (29.29%) were tested positive for Denguw Fever, out of which 414 patients were included in the study. Males (58%) outnumbered females (42%). 84.57% of the patients were in the age group of 16 to 60 years. Most common clinical presentations were fever (100%), headache (97%), bodyache (93%), nausea (85%), vomiting (63%), retro-orbital pain (49%), itching (43%), abdominal pain (42%), skin rashes (27%) and loose motion (26%). Pneumonia was seen in 10 % of patients. 90% of patients were admitted in the hospital and 3% required ICU admission. Around 10% of patients were managed as outpatient. Dengue Fever and Dengue Hemorrhagic Fever were present in 79% and 21% of the patients respectively. Only 2 out of 414 patients had Dengue Shock Syndrome. Thrombocytopenia (platelet count less than 100,000) was present in 70% of patients and 18% of patients had platelet count less than 50,000. Leucopenia was seen in 54% of patients. Most common ultrasound finding was hepatomegaly (31%) followed by thickened gall bladder wall and ascites (12% each), splenomegaly (9%) and pleural effusion (8%). Only one patient with DHF died during the course of treatment.

    Conclusion:

    Dengue is no more a stranger’s disease in Nepalese context and precautions are warranted when residing/travelling Nepal.


    Subject Category: T. Travel/tropical medicine and parasitology

    Arun Sedhain, MD, Internal Medicine, Medicine, Chitwan Medical College, Bharatpur, Nepal

    Disclosures:

    A. Sedhain, None

    Findings in the abstracts are embargoed until 12:01 a.m. EST Thursday, Oct. 20 with the exception of research findings presented at IDSA press conferences.