437. Hepatitis B Virus Infection Status and Awareness among Healthcare Personnel American Samoa, 2010
Session: Poster Abstract Session: Occupational Health
Thursday, October 18, 2012
Room: SDCC Poster Hall F-H

Background: Compared to the United States, the prevalence of hepatitis B virus (HBV) infection in American Samoa (A Samoa) is high; consequently healthcare personnel (HCP) have a significant risk of infection from accidental exposure to blood and bodily fluids. Although there are global recommendations for hepatitis B (HB) vaccination of HCP, A Samoa does not have a policy mandating vaccination prior to patient contact. To determine prevalence of HBV infection (past and present) and immunity, and to assess awareness of infection status, we interviewed and performed HBV testing among HCP in A Samoa in 2010.

Methods: Demographic, risk and clinical data were collected from consenting employees of the island's only hospital using a questionnaire. HBV status was determined by testing serum for anti-HBs, anti-HBc (total and IgM), and HBsAg. To assess validity of self-reported HB vaccination and infection status, we compared self-report with serology results.

Results: Overall, 231 (38.2%) hospital employees participated; 158 (68.4%) were HCP. Median age of participants was 38.5 [19-70] years, 73.2% were female, and average number of years in patient care was 10.7.

Among HCP, 72 (45.6%) reported past needle stick injury. Fifty-four (34.2%) reported receipt of ≥1 dose of HB vaccine, of which 28 (51.9%) had anti-HBs ≥10 mIU/mL. On serologic testing of HCP, 3 (1.9%) were chronically infected (total anti-HBc and HBsAg positive), 57 (36.1%) were susceptible (HBsAg, anti-HBc, and anti-HBs negative), 91 (57.6%) had anti-HBs ≥10 mIU/mL, of which 29 (31.9%) had evidence of prior exposure to HBV (total anti-HBc positive). Seventy-three (46.2%) reported prior HBV testing; 37 (50.7%) reported a test result and 26 (70.3%) correctly classified their status.

HCP more frequently reported prior HBV testing, HB vaccination, and past needle stick injury than non-HCP (p<0.05). There was no difference in the proportion with anti-HBs ≥10 mIU/mL between HCP and non-HCP (p=0.08).

Conclusion: A third of HCP were susceptible to HBV infection and only about one-half of those who reported ≥1 dose of HB vaccination had anti-HBs ≥10 mIU/mL. A comprehensive vaccination policy for A Samoan HCP including post-vaccination testing to determine protection should be developed.

Kathleen Ly, MPH1, Roxanne Williams, MD, MPH1, Henry Roberts, PhD1, Yolanda Masunu-Faleafaga2, Eyasu H. Teshale, MD1 and Jan Drobeniuc, MD, PhD3, (1)Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, (2)American Samoa Immunization Program, American Samoa Government Department of Health, Pago Pago, American Samoa, (3)Division of Viral Hepatitis, CDC, Atlanta, GA


K. Ly, None

R. Williams, None

H. Roberts, None

Y. Masunu-Faleafaga, None

E. H. Teshale, None

J. Drobeniuc, None

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