478. Infectious Diseases Symptoms in Pregnant Women and Their Babies
Session: Poster Abstract Session: Pediatric Infections: Bacterial and Parasite
Thursday, October 18, 2012
Room: SDCC Poster Hall F-H
  • 478_ID (1).jpg (2.3 MB)
  • Background:

    The incidence of symptomatic infection in pregnant women and infants is poorly established. Using a weekly, automated telephone survey, we assessed infectious diseases symptoms in pregnant women and their newborns.


    Infectious symptoms including cold, cough, fever, diarrhea and vomiting during pregnancy and after delivery were reported weekly using an automated 2-minute-long telephone survey. Use of antibiotics and visits to health care providers (HCP) were also ascertained. Participants were called up to five times on both Tuesday and Wednesday of each week; non-respondents were contacted in person or by email to compete the survey within three days. The survey was validated by interview within eight hours of the automated call for 20 randomly-selected participants.


    A total of 54 pregnant women have been followed for a total of 482 weeks overall (mean±sd: 9±7 weeks per mother); 20 babies have been followed for a total of 241 weeks (mean±sd:12±11 weeks per baby). Infectious symptoms occurred in 13% and 12% of follow-up weeks in mothers and newborns respectively. Pregnant mothers who reported being sick were most likely have had a cold (31% of reported sick days) or a cough (22% of sick days); vomiting, diarrhea or fever were less common (5%, 4% and 4% of sick days, respectively). Among sick babies, colds and coughs were common (46% and 29% of sick days, respectively); other symptoms were less common (vomiting, fever and diarrhea: 14%, 5% and 2%, respectively). Antibiotic use was rare in both mothers and infants (5% and 0% of sick days, respectively). A total of 16% of mothers and 50% of babies who reported being sick visited a HCP. The validation showed highly accurate reporting.


    Infectious symptoms - particularly colds and coughs in both pregnant mothers and infants - occur relatively often and infrequently result in a medical visit. The use of a short automated telephone survey is a practical and reliable method to ascertain weekly health status in pregnant women and infants over time.

    Catherine Ley, PhD1, Ting Ma, MS1, Janette Noveras, BS1, Maria de la Luz Sanchez, BS1 and Julie Parsonnet, MD, FIDSA2, (1)Stanford School of Medicine, Division of Infectious DIseases and Geographic Medicine, Stanford, CA, (2)Departments of Medicine and of Health Research and Policy, Stanford University, Stanford, CA


    C. Ley, None

    T. Ma, None

    J. Noveras, None

    M. D. L. L. Sanchez, None

    J. Parsonnet, None

    Findings in the abstracts are embargoed until 12:01 a.m. PST, Oct. 17th with the exception of research findings presented at the IDWeek press conferences.