116. Novel Approaches to RePOOPulating the Gut with Fecal Substitute Transplant Therapy
Session: Symposium: Relapsing Clostridium difficile Infection (CDI): When Standard Medical Therapy Fails
Thursday, October 3, 2013: 11:30 AM
Room: The Moscone Center: 104 (Gateway Ballroom)
Elaine Petrof, MD, Medicine, Queen's University, Kingston, ON, Canada

CURRICULUM VITAE
ELAINE O. PETROF, M.D., M.Sc.
Assistant Professor
Queen’s University
Dept. of Medicine
Division of Infectious Diseases
76 Stuart Street
GIDRU wing (Gastointestinal Diseases Research Unit)
Kingston, ON
K7L 2V7
Canada
PREVIOUS EMPLOYMENT
Instructor
Dept. of Medicine
Section of Infectious Diseases
University of Chicago
5841 S. Maryland Ave. (MC 6084)
Chicago, IL 60637
(July 2004-2007)
EDUCATION / TRAINING
UNDERGRADUATE
1986, Champlain Regional College, D.E.C. (Health Sciences)
1989, Universite Laval, B.Sc. (Biochemistry)
GRADUATE EDUCATION
1992, University of Ottawa, M.Sc. (Pharmacology)
1996, University of Toronto, M.D.
1999, University of Illinois at Chicago, Internal Medicine (Board Certification 1999)
2001, University of Chicago Fellowship, Infectious Diseases (Board Certification 2001)
2003, Fellowship in Clinical Pharmacology and Pharmacogenomics
SCHOLARSHIPS & AWARDS
2000, University of Chicago Immunology training grant.
2001-03, NIH training grant Clinical Pharmacology
2003, ASCPT, annual meeting, Top Abstract
2003, NIH K08 award (DK064840)
2004, Louis Block Award, University of Chicago
2004, NIH DDRCC Pilot & Feasibility Award DK42086
2006, Glaxo Smith Kline GIDH (Gastointestinal Diseases and Health) Award
2007, CSCR Clinician Scientist Award
2008, CAG New Investigator Establishment Award (declined)
2008, Crohn’s and Colitis Foundation of Canada Award
PUBLICATIONS & PRESENTATIONS
SELECTED PUBLICATIONS
Fournier PA. Petrof EO. Guderley H. The glucosidic pathways and glucose production by frog muscle. Journal of Biological Chemistry. 267(12):8234-7, 1992 Apr 25.
Petrof EO. Schwartz DN. Quinn JP. Urinary tract infections and a multidrug-resistant Escherichia coli clonal group. New England Journal of Medicine. 346(7):535-6, 2002 Feb 14.
Musch MW, Petrof EO, Kojima K, Ren H, McKay DM, and Chang EB. Bacterial superantigen treated intestinal epithelial cells upregulate heat shock proteins 25 and 72 and are resistant to oxidant cytotoxicity. Infection & Immunity 72: 3187-3194, 2004.
Petrof EO, Kojima K, Ropeleski MJ, Musch MW, Tao Y, De Simone C, and Chang EB. Probiotics inhibit NF-kB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition. Gastroenterology 127: 1474-1487, 2004.
Tao Y, Drabik KA, Waypa TS, Musch MW, Alverdy JC, Schneewind O, Chang EB and Petrof EO. Soluble factors from the probiotic Lactobacillus GG activate MAP kinases and induce cytoprotective heat shock proteins in intestinal epithelial cells. Am J Physiol Cell Physiol. 290(4):C1018-30, 2006. (Epub ahead of print Nov 2005).
Claud EC, Zhang X, Petrof EO, Sun J. Developmentally regulated tumor necrosis factor alpha induced nuclear factor kappaB activation in intestinal epithelium. Am J Physiol Gastrointest Liver Physiol, 292(5):G1411-9, 2007. (Epub ahead of print Feb 2007).
Zaborina O, Lepine F, Xiao G , Valuckaite V, Chen Y, Li T, Ciancio M, Zaborin A, Petrof E, Turner JR, Rahme LG, Chang E, Alverdy JC. Dynorphin Activates Quorum Sensing Quinolone Signaling in Pseudomonas aeruginosa. PLoS Pathogens 3(3): e35, 2007.
Ye Z, Petrof EO, Boone D, Claud EC, Sun J. Salmonella Effector AvrA Regulation of Colonic Epithelial Cell Inflammation by Deubiquitination. Am J Pathol., 171(3):882-92, 2007. (Epub ahead of print Aug 2007).
Petrof EO, Musch MW, Ciancio MJ, Sun J, Claud EC, Gewirtz A, and Chang EB. Flagellin is required for Salmonella-induced expression of heat shock protein Hsp25



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