389. PREVALENCE OF STAPHYLOCOCCUS AUREUS METHICILLIN SENSITIVE AND METHICILLIN RESISTANT NASAL AND PHARYNGEAL COLONIZATION IN OUTPATIENTS IN LEBANON
Session: Poster Abstract Session: MRSA, MSSA, Enterococci
Thursday, October 3, 2013
Room: The Moscone Center: Poster Hall C
Posters
  • Master_UHealth_poster_template_4x8[2][1][1][1][2][1].pdf (238.3 kB)
  • Background:  

    There is an increasing concern about MRSA infections, especially with the wide use of antibiotics , injected medications and abuse substances in the community. The aim of our study is to evaluate the rate of Staphylococcus aureus nasopharyngeal colonization in outpatients as primary endpoint, and to study the impact of several possible risk factors including recent hospitalization, recent surgical procedures and antibiotic intake.

    Methods: 

    1526 consecutive outpatients underwent surveillance cultures after filling a questionnaire.Isolated Staphylococcus aureus strains were tested for antibiotic susceptibilities. The Pearson Chi-square test was used for statistical analysis. The differences were considered to be statistically significant when P was <5%. If the significance was found , a subsequent logistic regression was followed in order to adjust for confusion factors.

    Results:  

    133 out of 1526 (8.7% ) were carriers of Staphylococcus aureus in their nose and/or throat. Only 2 of those were MRSA and both were isolated from the nose. 131 had MSSA with 13 of them present simultaneously in the nose and throat, while the rest (119 out of 131) had MSSA recovered from the nose only.

    Males were more likely [88 out of 718, (12.12%)] to be Staphylococcus aureus carriers than females [45 out of 808, (5.69%)] (p <0.001 , Khi-2 value was 21.57). A multivariate analysis was conducted, and the presence of an intravascular device or prosthesis was retained in the model: (chi-square of 8.59 and p-value = 0.01) in males . However, for females, none of the variables was retained.  

    Among the risk factors, presence of healthcare-relative ,intravascular device or prosthesis placement, recent dental procedure and use of health clubs were significantly associated with an increased risk of Staphylococcus aureus colonization with a calculated p value of 0.004, 0.017, 0.04 and 0.002 respectively by khi-2 test.

    Conclusion: 

    The prevalence of MRSA is still low in the population we sampled within the Lebanese community. The only identified significant risk factors playing a role in increasing the carriage of Staphylococcus aureus were associated related to healthcare exposure. Therefore, control measures to prevent the spread of MRSA should encourage reinforcement of hygienic precautions and development of policies to restrict the use of antibiotics.

    Maroun Sfeir, M.D., University of Miami/ Jackson Memorial Hospital, Miami, FL and Jacques Mokhbat, MD, University Medical Center-Rizk Hospital, Beirut, Lebanon

    Disclosures:

    M. Sfeir, None

    J. Mokhbat, None

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