1460. Changing Trends in Dengue Hemorrhagic Fever in Western Mexico. Experience from a Large Public Hospital
Session: Poster Abstract Session: Global Health
Saturday, October 5, 2013
Room: The Moscone Center: Poster Hall C
  • Changing Trends in Dengue.pdf (1.4 MB)
  • Background: Dengue is an emerging disease with increasing prevalence around the world. Over the last 15 years the cases of dengue hemorrhagic fever are seen most frequently in the metropolitan area of Mexico western. This paper reviews the changing epidemiology and clinical presentation of dengue hemorrhagic fever in a large hospital, comparing two outbreaks occurred in 2002 and 2009.

    Methods: We reviewed the clinical records of hospitalized patients with diagnosis of dengue hemorrhagic fever seen in the General West Hospital in Zapopan city on 2002 and 2009. We compared clinical, and epidemiological data of both groups. Stratified analysis and X2 analysis for trends were performed. 

    Results: 190 patients were seen in 2002, and 323 in 2009. Only 3.1% of the patients seen in 2002 were from the metropolitan area of Jalisco state while in 2009 it happened in 46.3%. The incidence was higher in the months of September to December in both groups, observing a great peak on October 2002 with 82 cases. There were no significant differences between the two groups (2002 vs 2009) in the mean years age with 31.6±17.2 vs. 33.4±17.2; a female gender of 27.3% vs 15.9%. The clinical manifestations were also similarly in both groups: fever 98% vs 98.1%; headache 97% vs 97.8%; myalgia 92% vs 99.6%; retro-ocular pain 76% vs 84.6%; petechial rash 55% vs 59.3%. The lab findings showed a mean hematocrit of 40% vs 42.2%; platelets of 35,000±27.8 vs 75,200±45.6 (P = 0.001); Hemoglobin (13 mg/dl vs 14.7 mg/dl). Mortality was low in both groups with 1% in 2002, and 0% in 2009.

    Conclusion: The present study confirmed a significant increase in the number of cases seen in the Metropolitan area of western Mexico in 2009 compared to 2002 (46.3% vs 3.1%, P= 0.001). There were minimal differences in clinical, and lab presentation. The mortality was very low in both groups.

    Gerardo Amaya-Tapia, MD, PhD1,2, Erika E. Delgado-Chavez, MD1, A. Cecilia Espinosa-Villaseņor, MD2, Nancy G. Canela-Bautista, MD2, David Diaz Santana-Bustamante, MD1, Juan Alberto Rodriguez-Ruiz, MD1 and Jaime Arias-Amaral, MD1, (1)Internal Medicine/ID, Hosp Gen De Occidente, Zapopan, Mexico, (2)Universidad De Guadalajara, Guadalajara, Mexico


    G. Amaya-Tapia, None

    E. E. Delgado-Chavez, None

    A. C. Espinosa-Villaseņor, None

    N. G. Canela-Bautista, None

    D. Diaz Santana-Bustamante, None

    J. A. Rodriguez-Ruiz, None

    J. Arias-Amaral, None

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