339. Influenza Vaccination in Chronically Ill Children: A Strategy to Improve Vaccination Coverage
Session: Poster Abstract Session: Influenza Vaccine in Children and Adults
Thursday, October 3, 2013
Room: The Moscone Center: Poster Hall C
  • InfluenzaVaccinationinChronicallyIllChildren_web.pdf (307.9 kB)
  • Background:  Routine vaccination of children with chronic illnesses, although important, is often suboptimal, in particular for annual influenza vaccination. We aimed to evaluate the implementation of an influenza vaccination clinic in a tertiary care hospital.

    Methods: As of October 2012, the province of Quebec recommended the preferential use of live-attenunated influenza vaccine (LAIV) for non-immunosuppressed children with chronic conditions and funded influenza vaccination clinics in pediatric tertiary care hospitals. This clinic was staffed with a nurse with expertise in vaccination and was opened from 8:30-16:30 (weekdays) from Oct.15 – Dec.21. Both trivalent inactivated vaccine (TIV) and LAIV were offered. Upon vaccination, parents were asked to fill a pre-piloted questionnaire. Specific denominators are presented for each question.

    Results:  A total of 630 patients with chronic illnesses were vaccinated against influenza during the campaign; 437 (69%) with LAIV. Of the 600 participants for whom the information was available, 88 (14.6%) were considered immunocompromised. Of the 582 participants for whom the information was available, only 311 (53.4%) had been vaccinated against influenza in the previous year. Of 589 parents who answered, 110 (18.7%) said that their child only received their influenza vaccine because of its availability on site. The vast majority of parents would have preferred LAIV over TIV (403/512; 78.7%) for their child. Of the 388 parents whose child received LAIV who answered, 223 (57%) said LAIV was better because there was no needle involved; 175 (45%), it was less painful and, in 116 (30%), it was considered more efficacious. In 27% of cases (110/388), parents made this choice based on their physicians’ suggestion. In addition to the child with chronic illness, 369 family members (parents-siblings) were also vaccinated. 

    Conclusion: Yearly influenza vaccination is recommended for children with chronic illnesses. However, vaccination is often not a priority for their treating physicians and strategies to facilitate vaccination are necessary. Having an influenza vaccination clinic on site (where children are coming for their scheduled visits) for children and their families, using LAIV preferentially when indicated, is well received and improves vaccination coverage.

    Joanna Merckx, MD1, Eve Dubé, PhD2, Nicole Boulianne, BSc(N), M.Sc2, Monique Landry, MD3, Louise Valiquette, MD3, Deirdre Mccormack, BSc(N)4 and Caroline Quach, MD MSc1,4,5,6, (1)Division of Infectious Diseases; Department of Pediatrics, The Montreal Children's Hospital, Montreal, QC, Canada, (2)Institut National De Santé Publique Du Québec, Quebec, QC, Canada, (3)Ministère De La Santé Et Des Services Sociaux Du Québec, Montreal, QC, Canada, (4)Vaccine Study Centre, Research Institute of the Mcgill Univ. Health Centre, Montreal, QC, Canada, (5)Institut National De Santé Publique Du Québec, Montreal, QC, Canada, (6)Epidemiology, Biostatistics, and Occupational Health, Mc Gill University, Montreal, QC, Canada


    J. Merckx, None

    E. Dubé, None

    N. Boulianne, None

    M. Landry, None

    L. Valiquette, None

    D. Mccormack, None

    C. Quach, None

    Findings in the abstracts are embargoed until 12:01 a.m. PST, Oct. 2nd with the exception of research findings presented at the IDWeek press conferences.