1425. Clinico-radiological Manifestations of Neurocysticercosis: A Tertiary Care Study
Session: Poster Abstract Session: CNS Infections
Saturday, October 5, 2013
Room: The Moscone Center: Poster Hall C
  • NCC.pdf (959.0 kB)
  • Background: Neurocysticercosis (NCC) is a common infection in tropical countries like India. It is one of the important causes of seizures and accounts for one-third cases of epilepsy in the country. It is one of the treatable causes of seizures in adults. This study tries to address the clinical presentation and outcomes of NCC.

    Methods: We have retrospectively studied all patients who were diagnosed to have NCC as per del Brutto’s criteria from January 2000 to December 2012 at Kasturba Medical College, Manipal, India. In this study, we have focused our attention to clinical presentations, radiological manifestations and outcomes.

    Results: A total of 68 patients were included in the study. The mean age of presentation was 28.76 years with a male preponderance (n=54; 79.41%). Majority of patients presented with seizures (n=54; 79.41%) of which generalized tonic-clonic seizures (n=45; 66.17%) was the commonest type. Other common presenting symptoms were headache (n=14; 20.58%) and visual symptoms (n=6; 8.82%). On imaging, majority of patients had a solitary lesion (n=45; 66.17%) and most common site for the lesion was frontal and parietal area. A confirmed diagnosis was made in 28 (41.17%) patients and a probable diagnosis in 40 patients (68.96%). A total of 61 (89.70%) patients received treatment, out of which albendazole was administered in 58 (85.29%) patients and steroids in 50 (73.5%) patients. Majority of patients (n=66; 97.05%) were initiated on anti-epileptic drugs. 24 (35.29%) patients had complete resolution of the primary lesion. At the end of 1 year follow up, 60 (88.23%) patients were seizure free. 

    Conclusion: NCC should be suspected, investigated and promptly treated for all patients presenting with seizures in tropical counties.

    Apurva Bansal, MBBS1, Surya Narayana, MBBS1, Danturulu Muralidhar Varma, MD2 and Sudha Vidyasagar, MD3, (1)Kasturba Medical College, Manipal University, Manipal Karnataka, India, (2)Department of Medicine, Kasturba Medical College, Manipal University., Manipal Karnataka, India, (3)Medicine, Kasturba Medical College, Manipal Karnataka, India


    A. Bansal, None

    S. Narayana, None

    D. M. Varma, None

    S. Vidyasagar, None

    See more of: CNS Infections
    See more of: Poster Abstract Session

    Findings in the abstracts are embargoed until 12:01 a.m. PST, Oct. 2nd with the exception of research findings presented at the IDWeek press conferences.