1490. Prevalence of HIV in Filipino TB patients: Implications for Scale-up of Screening and Surveillance Efforts
Session: Poster Abstract Session: Global HIV
Saturday, October 5, 2013
Room: The Moscone Center: Poster Hall C
Posters
  • Roa TB HIV poster.pdf (132.2 kB)
  • Background:

    The Philippines is one of 22 countries with a high tuberculosis (TB) burden, and is one of nine countries with an increasing prevalence of HIV infection. National TB guidelines have proposed universal HIV screening in TB patients, but no published literature supports this. Our study aimed to determine the prevalence of HIV co-infection in patients with tuberculosis to provide evidence to support or refute this assertion.

    Methods:

    Following institutional review board approval, a point prevalence survey was done among consecutive adult TB patients who gave consent to HIV testing (regardless of risk) at our tuberculosis outpatient clinic, and in the wards at the Philippine General Hospital (PGH). PGH is the largest tertiary-care government hospital in the country and is a national referral center. Screening was done using ELISA/ECLIA testing (Abbott Architect HIV Ag/Ab) with Western blot for confirmation. Data was analyzed using Microsoft Excel 2007.

    Results:

    101 patients with clinical and/or laboratory-diagnosed TB were screened for HIV. Mean age was 41 years old (SD=13.64). 63 were men and 38 were women.  46% had pulmonary TB (PTB), 41% had extra pulmonary TB (EPTB), and 14% had both PTB and EPTB. The most common EPTB sites were the vertebrae (22%) and lymph nodes (22%). Only 7% had previous HIV screening.  Of the 84 patients who admitted to sexual contact, 46% had multiple lifetime partners, and 74% had never used condoms.   All except one male was circumcised.

    Three patients were found to be HIV-positive. All were male, single, with multiple sexual partners, and no history of STDs. Two were heterosexual while one was bisexual.  All denied illicit drug use. Their ages and TB sites were 36 (TB adenitis), 53 (PTB), and 30 (PTB and gastrointestinal TB). All three were circumcised.

    Conclusion:

    We report an HIV point prevalence of 3% among consecutive Filipino TB patients in our hospital. This is much higher than the 0.1% cutoff recommended for universal screening of a population at risk, and very much higher than the general population prevalence of 0.01%. This study is limited by the fact that this was done in only one hospital, but it nevertheless provides robust data to support universal HIV screening for TB patients in the Philippines.

    Kathryn Roa, MD, MPH, Marbe Depayso, MD, Kristine Bajandi, MD, Marissa Alejandria, MD, Jodor Lim, MD and Edsel Maurice Salvana, MD, Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines

    Disclosures:

    K. Roa, None

    M. Depayso, None

    K. Bajandi, None

    M. Alejandria, None

    J. Lim, None

    E. M. Salvana, None

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