1760. Trends in HIV/hepatitis C (HCV) co-infection among men who have sex with men (MSM) in New York City (NYC), 2000-2010
Session: Poster Abstract Session: Viral Infections; Pathogenesis and Epidemiology
Saturday, October 5, 2013
Room: The Moscone Center: Poster Hall C
Background: Outbreaks of hepatitis C virus infection (HCV) among HIV-infected MSM have been reported in New York and other cities, suggesting that MSM may be at risk of acquiring HCV sexually. We examined trends and characteristics of persons with both an HIV and HCV report in NYC, comparing MSM to non-MSM. 

Methods: The New York City (NYC) Department of Health and Mental Hygiene (DOHMH) implemented CDC’s Program Collaboration and Service Integration (PCSI) initiative to improve understanding of infectious diseases in NYC.  We conducted a retrospective, deterministic cross-match of NYC’s HIV and chronic HCV surveillance data from 2000-2010, and vital statistics data from 2000-2011. We restricted our analysis to persons diagnosed and living with HIV/AIDS (PLWHA) who were alive as of January 1, 2000 and subsequently diagnosed with HCV. We analyzed demographic characteristics and timing of diagnoses of persons with reports of HIV and HCV.  Using survival analysis, we compared progression to death between the MSM and non-MSM groups over the 10-year period, controlling for demographic factors.

Results: There were 140,685 PLWHA in NYC in 2000; 16% of these (N=23,101) were reported with a HCV diagnosis during the study period.  In 2000, 8% of PLWHA diagnosed with HCV were MSM; in 2010, 31% were MSM. Among persons with HIV and HCV infection, 34% of MSM were white compared with 12% of non-MSM; 47% of MSM cases lived in Manhattan compared with 25% of non-MSM.  MSM cases were more likely to have other sexually transmitted diseases such as hepatitis B and syphilis. MSM cases were less likely to have died (18%) during the study period than non-MSM (37%).  In survival analysis, MSM were half as likely to progress to death as non-MSM (p<.0001).

Conclusion: The prevalence of HCV co-infection is increasing among HIV-infected MSM, although this may partly be because they live longer than co-infected persons with other HIV risk factors such as injection drug use. Future research is necessary to confirm if sexual transmission of HCV is increasing among HIV-infected MSM.

Ann Drobnik, MPH1, Jessie Pinchoff, PhD Candidate, MPH1, Jennifer Fuld, PhD Candidate, MA1, Katherine Bornschlegel, MPH2, Jay Varma, MD1 and Sarah Braunstein, PhD, MPH3, (1)Division of Disease Control, New York City Department of Health and Mental Hygiene, Long Island City, NY, (2)Bureau of Communicable Diseases, New York City Department of Health and Mental Hygiene, Long Island City, NY, (3)Bureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene, Long Island City, NY

Disclosures:

A. Drobnik, None

J. Pinchoff, None

J. Fuld, None

K. Bornschlegel, None

J. Varma, None

S. Braunstein, None

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