371. Epidemiology of Staphylococcus aureus Colonization in Health Workers in Lima, Peru
Session: Poster Abstract Session: MRSA, MSSA, Enterococci
Thursday, October 3, 2013
Room: The Moscone Center: Poster Hall C

There is limited information on epidemiology of Staphylococcus aureus colonization in health care workers and hospitalized patients in resource limited settings. This information is essential for treatment and control strategies.


The study was done in a 400 bed hospital in Lima, Peru. Health care workers of a surgical unit were evaluated by anterior nares cultures for prevalence of S. aureus nasal colonization. The population included nursing and medical students, nursing staff, interns, residents and attendings. Demographic characteristics were collected including gender, age, occupation, time of service, time spent in campus, previous MRSA patients exposure, previous MRSA infection. Molecular analysis was conducted to determine molecular epidemiology using pulse field gel electrophoresis (PFGE).


171 health care workers were evaluated between September and October in 2012. The mean age was 27.3 years (18 – 65y), most of the subjects were female (78.4%). A total of 104 (60.8%) were nurses, 23(13.4%) were nursing students, 21 (12.3%) were internal medicine interns on their General Surgery  rotation, 13 (7.6%) were medical students, 9 (5.3%) were residents and only one (0.6%) attending accepted to participate. 87 % of the participants had been working in the inpatient setting for less than 5 years. 81.3 % spent between 7-12 hours/day in the hospital. Most of the participants (63.7%) had never cared for a known MRSA patient, only one had an MRSA infection before and none had used antibiotics in the previous 90 days. Overall 34 (20%) health workers were colonized with S. aureus, 7 (21%) of S. aureus were MRSA. Molecular evaluation of strains showed there were six different strain types of MRSA: none were USA300 all were non USA100-1100 strains indicating unique strain types. Of the MSSA strains, 18 were non USA 100-1100, three were USA 600, two USA 300, two USA 100, one USA 200 and one was unidentifiable.


Staphylococcus aureus colonization rates in low income settings are low relative to those reported in the United States and even on other Latin-American countries. Particularly the community MRSA (USA300) strain type was uncommon in both groups. This information will be of use to gain a better understanding of epidemiology and determine the risk factors affecting colonization.

Claudia Taramona, MD1, Ashley Hall, PharmD, MPH2, Daniela Moreno, B.S.2, Daniella Angulo, MD3, Lizeth Astocondor, MT4, Gertrudis Horna, Lic MT4, Laura Mori, MD5,6, Mary Perri, MT2, Coralith Garcia, MD4 and Marcus Zervos, MD2, (1)Henry Ford Hospital, Detroit, MI, (2)Infectious Diseases, Henry Ford Hospital, Detroit, MI, (3)Internal Medicine, Henry Ford Hospital, Detroit, MI, (4)Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru, (5)Departamento Académico de Ciencias Celulares y Moleculares, Facultad de Ciencias y Filosofía Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Peru, (6)Unidad de Análisis y Generación de Evidencias en Salud Pública (UNAGESP), Instituto Nacional de Salud (INS), Lima, Peru


C. Taramona, None

A. Hall, Optimer Pharmaceuticals, Inc.: Employee, Salary
Cubist Pharmaceuticals: Speaker's Bureau, Speaker honorarium

D. Moreno, None

D. Angulo, None

L. Astocondor, None

G. Horna, None

L. Mori, None

M. Perri, None

C. Garcia, None

M. Zervos, None

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