951. The risk for Group B strepococcal infection is markedly increased?
Session: Poster Abstract Session: Sexually Transmitted Infections
Friday, October 4, 2013
Room: The Moscone Center: Poster Hall C
Background:

Group B streptococcus, known as Streptococcus agalactiae, has regarded as one of important pathogen of urinary tract infection in adults since 1990's and sometimes causes serious infection in older persons and those with chronic medical illness. Thus, this study would investigate the clinical characteristic of group B streptococcal UTI compared that due to E.coli

Methods:

This study is designed as the retrospective case-control study. Among 3721 UTI cases diagnosed between May 2002 and May 2013, a total of 41 patients were confirmed as group B streptococcal UTI. A sex and age-matched group of patients diagnosed as E. coli UTI in same period were selected as a control group. Several clinical characteristics including underlying disease, symptoms, laboratory result and imaging study were analyzed.

Results: The mean age of the patients (36 women, 5 men) was 62.3 years and thirty-five of 41 patients had at least one underlying condition; the most frequent were menopause (69.4%), cardiovascular disease (41.5%) and diabetes mellitus (31.7%). Previous history of UTI and underlying chronic kidney disease including end stage renal disease on hemodialysis were statically significant risk factors compared to patient group of E. coliUTI. More patients of E. coli UTI were showed fever (100% vs 65.8%) and flank pain (65.8% vs 24.4%). In laboratory results, lowered percentage of segmented WBC and platelet count (p value <0.001 and <0.01) and more polymicrobial reports of urine culture study (p value <0.001) were showed in patients of group B streptococcal UTI. There was no group B streptococcal bacteremia. In antimicrobial susceptibility test, one case was reported as a resistant strain for penicillin, oxacillin, gentamicin and erthryomycin; another three cases showed resistance for clindamycin. Almost patients of group B streptococcal UTI were well treated by cephalosporins(41.5%), quinolines(26.8%) and penicillins (9.8%). There was no significant difference in result of imaging study and number of deaths.

Conclusion:

In comparison with E. coli UTI, group B streptococcal UTI manifested more underlying risk factors including previous UTI history and chronic kidney disease. Additionally, we should give attention to the one case resistant for penicillin and oxacillin.

Sang Hoon Lee, Internal Medicine, Severance hospital, Seoul, South Korea and Yoonseon Park, MD, ID, NHIS Ilsan hospital, Gyeonggi-do, South Korea

Disclosures:

S. H. Lee, None

Y. Park, None

Findings in the abstracts are embargoed until 12:01 a.m. PST, Oct. 2nd with the exception of research findings presented at the IDWeek press conferences.