318. Reduction in Virus Transmission in Homes with Use of an Alcohol-Based Hand Rub
Session: Poster Abstract Session: Hand Hygiene in Healthcare Settings
Thursday, October 3, 2013
Room: The Moscone Center: Poster Hall C
  • IDweek 2013 PURELL promise poster.final.pdf (2.6 MB)
  • Background: Most of the clinical data generated supporting the efficacy of alcohol-based hand rubs (ABHR) has been collected in settings outside of the home.  There is little known about how use of an ABHR in the home will impact transmission of microbes between people and to fomites.  The objective of this study was to determine the impact of using an ABHR on reduction of virus transmission in homes.

    Methods: Seven homes in the Tucson, AZ area with families including at least 2 children under 18 were studied.  In each home a baseline phase was conducted where 1 x 108 of the bacteriophage MS-2 was inoculated onto the hands of one adult household member.  All other household members received inoculum without MS-2.  After 8 hours the fingers of all household members and >25 high touch surfaces in the home were assayed for surviving MS-2.  In the intervention phases this was repeated except all members of the household were instructed to use a 70% ethanol ABHR at least once or at least three times in the 8 hour period.  For both the 1 time and 3 times per day groups, log10 reductions from baseline were calculated and statistical analysis was conducted.

    Results: During the baseline phase of the study all assayed surfaces in the home and the fingers of all people showed contamination.  There was a significant reduction (P<0.0005) in virus transferred to hands of people who were not originally contaminated with 1 use and 3 uses per day, 99.7% and 98.9%, respectively. Virus on hands of people who were contaminated was significantly reduced (P<0.0005) at 1 use and 3 uses by 99.8% and 99.7%, respectively.  There was also a significant reduction in transfer to environmental surfaces, including those in the bathroom, kitchen, living area, and on phones for both the 1 use and 3 uses per day groups (P<0.0005). Additionally, in the intervention phase, the amount of virus remaining on many fomites was below the limit of detection.

    Conclusion: Use of an ABHR by all family members at least one time per day was enough to significantly reduce viral load in the household and the transfer of virus to other family members and to fomites.  This data indicates that use of an ABHR in households may be an effective intervention for reducing the risk of illness transmission between household members.

    Sarah Edmonds, MS1, Sheri Maxwell, BS2, Akrum Tamimi, PhD2 and Charles Gerba, PhD2, (1)GOJO Industries, Inc, Akron, OH, (2)University of Arizona, Tucson, AZ


    S. Edmonds, GOJO Industries: Employee, Salary

    S. Maxwell, None

    A. Tamimi, None

    C. Gerba, GOJO Industries: Collaborator, Research support

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