939. Ventilator-associated pneumonia caused by Stenotrophomonas maltophilia in pediatric patients
Session: Poster Abstract Session: Respiratory Infections
Friday, October 4, 2013
Room: The Moscone Center: Poster Hall C
Background: Ventilator-associated pneumonia (VAP) is a serious threat in critically ill pediatric patients.  Data regarding associated VAP caused by Stenotrophomonas maltophilia in pediatric population is limited.

Methods: A retrospective chart review was performed in pediatric patients 18 years old or younger who developed the first episode of S. maltophilia associated VAP at Samsung Medical Center, Seoul Korea from January 2008 to December 2012.

Results: A total of 45 patients were identified with VAP caused by S. maltophilia. Median age was 1.9 years (range, 0.1 to 18.8 years) and 24 patients were male (53.3%). Underlying illnesses were hematologic oncologic malignancy (n=14, 31.1%28.9%), cardiologic diseases (n=13, 28.97%), neurologic diseases (n=9, 20.0%), pulmonary diseases (n=5, 11.1%), and others (n=4, 8.9%). The median duration of ventilator treatment before VAP was 21 days (range, 3-255 days). Two patients also developed S. maltophilia bacteremia (4.4%). Overall mortality at 30 days was 6.7%. 

Conclusion: S. maltophilia should be also considered as a possible pathogen for VAP in critically ill pediatric patients. Empiric antibiotic choice should include agents that are active against S. maltophila in patients who are deteriorating on broad spectrum beta-lactam antimicrobial agents.

Byung-Kee Lee, MD1, Joong Bum Cho, MD1, Soo Jin Kim, MD1, Soo-Han Choi, MD2, Kang-Mo Ahn, MD, PhD1, Hong Eo, MD, PhD3, So-Young Yoo, MD, PhD3, Ji Hye Kim, MD, PhD3, Nam Yong Lee, MD, PhD4 and Yae-Jean Kim, MD, PhD1, (1)Department of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea, (2)Clinical Science Department (Pediatrics), Graduate School of Medicine, Sungkyunkwan University, Seoul, South Korea, (3)Department of Radiology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea, (4)Department of Laboratory Medicine and Genetics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea

Disclosures:

B. K. Lee, None

J. B. Cho, None

S. J. Kim, None

S. H. Choi, None

K. M. Ahn, None

H. Eo, None

S. Y. Yoo, None

J. H. Kim, None

N. Y. Lee, None

Y. J. Kim, None

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