1646. Prevalence of respiratory symptomatic subjects and risk factors of TB in outpatient facilities in Lima and Callao
Session: Poster Abstract Session: Mycobacterial Infections
Saturday, October 5, 2013
Room: The Moscone Center: Poster Hall C
Background: Tuberculiosis (TB) is still a major health problem. Prevention programs are mostly based on the early detection of cases through the screening of respiratory symptomatic subjects (RSS). We aimed to assess the frequency of RSS and the risk factors for pulmonary TB diagnostic among them, in outpatient facilities in Lima and Callao, Peru.

Methods: cross-sectional study in 15 years old or older patients, who attended the outpatient or emergency service of health centers between March and August 2012. The study consisted of two phases. In the first, we gather sociodemographic information and identify RSS. In the second phase, we collected demographic and clinical data, and a sample of sputum for smear exam, culture, MODS and DNA extraction in RSS. We calculated frequencies and summary measures. In bivariate analysis ORs were calculated with 95%CI and x2 tests or Fisher and Student T were used to estimate the association with a significance level of 0.05. The study was approved by the ethics committee of the National Institute of Health and all enrolled participants signed an informed consent

Results: 10421 persons were interviewed in the first phase, the mean age was 36.98±17.47 years, 77.2% were female, among which 23.5% were pregnant. 2.7% (IC 95% 2.4-3.0) of consultants had productive cough for seven or more days and 1.1% (IC 95% 0.9-1.3) for 15 or more days. 222 people were enrolled in the second phase; mean age was 41.8±18.9 years, 72.1% were female. There were 11 smear positive results, also 11 positive cultures and 7 positive MODS, with a total of 15 cases of TB (7%), 2 of them were multidrug resistant TB. There was an association between a TB and district DISA Lima Este (OR = 4.1, 95% CI [0.4 to 47.1], p = 0.049) as well as currently being in contact with someone with TB (OR: 74.3, 95% CI [3.4 to 1625.4], p = 0.005) or have previously been (OR: 3.1, 95% CI [1.0 to 9.3], p = 0.033). In the two hospitals were surveyed  5698 consultants, 2.2% of whom had productive cough for seven or more days and 1.4% for 15 or more days. We included 53 people, finding two cases of tuberculosis (3.8%).

Conclusion: The frequency of respiratory symptoms in first level health centers was 1.1%. The risk factors identified were having tuberculosis and have been in contact with a person with tuberculosis, as well as attend to the DISA Lima Este health centers.

Romina Tejada, MSc1, Lely Solari, MSc1, Jorge Alarcón, MSc2 and Julia Piscoya, MD3, (1)Unagesp, Instituto Nacional de Salud, Lima, Peru, (2)Instituto de Medicina Tropical "Daniel A. Carrión" - UNMSM, Bellavista, Peru, (3)Instituto de Medicina Tropical, Bellavista, Peru

Disclosures:

R. Tejada, None

L. Solari, None

J. Alarcón, None

J. Piscoya, None

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