Program Schedule

726
Readmission rate associated with Staphylococcus aureus bacteremia

Session: Poster Abstract Session: Bacteremia: Staphylococcal Bacteremia
Friday, October 10, 2014
Room: The Pennsylvania Convention Center: IDExpo Hall BC
Posters
  • IDweek 2014 SAB poster final2.pdf (248.4 kB)
  • Background: Staphylococcus aureus bacteremia (SAB) is one of the most common blood stream infections resulting in significant mortality and morbidity. The objective of the study was to evaluate outcomes in patients with SAB.

    Methods: We conducted a retrospective chart review of the patients who were admitted to the hospital in 2013, whose blood culture was positive of S. aureus. Outcomes evaluated were mortality, follow up blood cultures, length of stay (LOS), rate of readmission due to another SAB, and all-cause 30-and 60-day readmission rates. Statistical analyses were performed with SPSS software and Microsoft Excel software, with continuous and nominal data evaluated with the student t test and the Х2 test, respectively.

    Results:

    One hundred seven patients were identified to have 119 inpatient encounters associated with SAB.  Mortality during index hospital stay was 18%. Among the survivors, 25% didn’t have confirmatory negative culture obtained prior to discharge. Length of stay (LOS) was significantly shorter in patients who didn’t have negative blood culture compared to patients who had negative culture (5.2 days vs. 14.9 days, P<0.0001). Eleven percent of patients had readmissions with another SAB during the study period.  All-cause 30- and 60-day readmission rates were 26% and 39%, respectively. Fifty seven percent of 60 days readmissions were due to an infection and 17 % was secondary to primary SAB, such as allergic reaction to antibiotic, acute kidney injury, intravascular line issues, and/or opportunistic infections.  Overall, readmissions associated with infections accounted for 75% of 60 day readmissions. Among the survivors, Methicillin Resistant S. aureus (MRSA) group had higher rate of readmissions in 60 days compared to Methicillin Susceptible S. aureus (MSSA) group (50% vs 26%, P=0.028).

    Conclusion:

    In patients who had index admission for SAB, readmission rate with another SAB was 11%.  All-cause readmission rates were 26% and 39%, respectively in 30 days and 60 days, and up to 75% of 60 days readmissions were related to the primary SAB.

    Jean Lee, PharmD1, Su Lee, PharmD2, Colby Miller, PharmD1 and John Cmar, M.D.3, (1)Inpatient Pharmacy, Sinai Hospital of Baltimore, Baltimore, MD, (2)School of Pharmacy, University of Maryland Estern Shore, Princess Anne, MD, (3)Internal Medicine, Sinai Hospital of Baltimore, Baltimore, MD

    Disclosures:

    J. Lee, None

    S. Lee, None

    C. Miller, None

    J. Cmar, None

    Findings in the abstracts are embargoed until 12:01 a.m. EDT, Oct. 8th with the exception of research findings presented at the IDWeek press conferences.

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