Program Schedule

Impact of active surveillance program to control VRE in a university hospital with low endemic rates

Session: Poster Abstract Session: Outbreaks
Friday, October 10, 2014
Room: The Pennsylvania Convention Center: IDExpo Hall BC
  • id week 2014 abstract 46274.pdf (390.1 kB)
  • Background: Several different strategies have been implemented to control VRE in hospitals outbreaks. From 2007 to 2009, a VRE outbreak in our hospital was controlled with: active surveillance of rectal swabs, isolation of colonized/infected patients, barrier precautions, and antibiotic policies. Since 2009 the same protocols have being continuously implemented. This study evaluated the impact of maintaining the protocols for reducing VRE colonization/infection from January 2010 to February 2014 compared to the data from 2007 to 2009

    Methods: In 2007, 2.3 VRE cases (colonized + infected) per 1.000 pts-days were identified. With the implementations of control measures, in 2008-09, the incidence of density (ID) decreased to 0.83 cases per 1.000 pts-days (p<0.001). This prospective study was conducted in a tertiary care university hospital performing active surveillance of rectal swabs, isolation and barrier precautions for VRE colonized/infected patients. Rectal swabs were screened for VRE in patients with > 7 days of hospitalization or when patients were transferred in from other hospitals. The ID, incidence of new cases (colonized + infection) and infections for each biennium were evaluated and compared to the data from 2007-09. Statistical analyses were performed using Chi Square and exact Mid-P tests

    Results: 4,993 rectal swabs were collect and from 2010-11 and 3,128 from 2012-14.  During 2010-11 and 2012-14, 122 and 157 new cases were diagnosed respectively; ID were 0.48 and 0.55 new cases per 1000 patient-days and the incidence of new cases per 1000 admission were 4.13 and 4.84. A significant decrease in the incidence of new cases from 2007-09 to 2010-11 (6.98 vs.0.48; p<0.001) and in the ID (0.83 vs. 0.48; p<0.001) was observed. No differences were noted in the incidence of infections (0.43 vs. 0.34; p=0.17) in the two periods. No differences were observed in 2012-14 compared to the other periods

    Conclusion: The significant reduction in the incidence of new cases of VRE after the control of the first epidemic period (2007-09) suggested that the strategies implemented to control the VRE outbreak, in our hospital, should be maintained to keep endemic rates low

    Luis Gustavo De Oliveira Cardoso1, Renata Fagnani1, Mirtes Leichsenring1, Sonia Dantas1, Luis Felipe Bachur1, Christian Hoffling1, Plinio Trabasso2 and Maria Luiza Moretti2, (1)Hospital & Clinics, University of Campinas, Campinas, Brazil, (2)University of Campinas, Campinas, Brazil


    L. G. D. O. Cardoso, None

    R. Fagnani, None

    M. Leichsenring, None

    S. Dantas, None

    L. F. Bachur, None

    C. Hoffling, None

    P. Trabasso, None

    M. L. Moretti, None

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