Evaluation of Circulating sCD200 (OX-2), High Sensitive C-reactive Protein and Sedimentation Rate in Diabetic Foot Patients
Methods: The study was performed with 32 diabetic foot infection patients and 25 healthy control patients. sCD200 concentrations were quantified by using ELISA kit.
Results: We found that sCD200 levels in diabetic foot patients were higher than control group (124.79±4.22 vs 21.57±1.11 [mean±SEM], p<0.0001). However there is no correlation between sCD200 levels and the Hba1c levels, blood glucose levels (pre/postprandial) and BMI these markers. The hs-CRP levels and sedimentation rates were higher in patient group (p<0.0001, p<0.005 and p<0.0001 respectively).
Conclusion: To the best of our knowledge, this is the first study to assess serum sCD200 in diabetic patients with the late complication of diabetic footinfection.We investigated evidence for possible correlations between serum CRP levels, hs-CRP, and HbA1c, pre-prandial glucose levels BMI, WGS, and sedimentation rate. The sCD200 levels did not correlate with any of these markers.
G. E. Genc, None
F. Kizilates, None
S. Gumuslu, None