Antimicrobial efficacy of Corning® Gorilla® Glass 3 under laboratory conditions
The use of cellular phones and tablet computers has become widespread in the clinical environment. These hand-held devices can be contaminated with microorganisms and be a potential source for transmission of pathogens between healthcare workers and patients. We assessed the antimicrobial activity of silver-impregnated Corning® Gorilla® Glass 3 (Corning Incorporation, USA) against common nosocomial pathogens. This antimicrobial glass can be installed on display panels in mobile electronic devices.
Approximately 104 cfu bacteria (MRSA, Klebsiella pneumoniae) suspended in low-level organic soiling (0.03% bovine serum albumin) was inoculated onto a control (without silver) or test (antimicrobial) glass surface (25 cm2) and covered with a microscope glass slide. After the appropriate contact time (0.25, 30, 60 minutes and 3, 5, 24 hours) each test area was sampled with a pre-moistened cotton swab, plated on Columbia blood agar and incubated at 37oC for 24hours prior to reading. Tests were replicated six times.
MRSA and K. pneumoniae recovered from the antimicrobial glass surfaces in the presence of low-level soiling was statistically significantly less (p=0.02 and p<0.001, respectively) than from control glass after 30 minutes contact time. The antimicrobial glass surface reduced MRSA contamination by 2.81log10 demonstrating 99.8% reductions after 3 hours contact time and to below the detection limit (2 cfu/25cm2) within 24hours. Contamination with K. pneumoniae was reduced by 3.19log10(99.96% reduction) within 3 hours contact-time and reduced to below the detection limit on antimicrobial glass surface after 5 hours contact time.
Under laboratory conditions, silver-impregnated antimicrobial glass (Corning® Gorilla® Glass) can effectively reduce MRSA and K. pneumoniae contamination from treated glass surfaces even under low-level soiling and without mechanical cleaning. The reduction of bacteria from items such as tablet devices will reduce the likelihood of these surfaces becoming potential reservoirs for bacterial transmission in the clinical environment.
Corning Incorporation: Investigator, Research support
P. Wilson, Corning Incorporation: Consultant, Research support