Program Schedule

766
Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection

Session: Poster Abstract Session: Clinical Respiratory Infections
Friday, October 10, 2014
Room: The Pennsylvania Convention Center: IDExpo Hall BC
Background:

The number of laboratory confirmed cases of Middle East Respiratory Syndrome- Corona Virus is increasing and has been associated with high mortality rate. Our aim is to describe clinical features and outcome of patients infected with MERS CoV in a tertiary hospital outbreak in Jeddah, Saudi Arabia.

Methods:

We reviewed the medical records of 30 patients with confirmed MERS CoV infections during hospital outbreak between April 7th until April 30th 2014. We followed WHO definitions for confirmed MERS CoV infection. 

Results:

A total of 30 patients were diagnosed with confirmed MERS CoV infection. 16 patients were health care workers. The mean age was 43 years (SD 16.5). Seventeen patients were male (54.8%). Majority of patients N=20 (66.7%) were symptomatic on presentation. Fever was the most presenting symptoms N=20 (66.7%) followed by cough N=18 (60%). Although only 10 patients (35.7%) reported shortness of breath on presentation, 27 patients (93.1%) had abnormal chest xary. In terms of laboratory findings, 13 patients (54.2%) had lymphopenia on presentation. Significant number of patients developed progressive respiratory disease; 9 patients (30%) required mechanical ventilation and 12 patients (38.7%) required ICU admission. 

Conclusion:

Fever and abnormal chest x ray were the most common clinical features in patients with MERS CoV infection. Significant number of MERS CoV patient’s required mechanical ventilation and ICU admission.

Basem Alraddadi, MD, MS, Noha Bawareth, MD, Haneen Omar, Hanadi Alsalmi, MS, Maun Feteih, MD and Ghassan Wali, MD, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia

Disclosures:

B. Alraddadi, None

N. Bawareth, None

H. Omar, None

H. Alsalmi, None

M. Feteih, None

G. Wali, None

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