1725. An Audit of Pediatric Sepsis in a Tertiary Centre from a Developing Country from 2010 to 2014 using Administrative Data
Session: Poster Abstract Session: Infection Prevention: Infection Prevention in Resource Limited Environments
Saturday, October 10, 2015
Room: Poster Hall
Background:

Sepsis is a global cause of morbidity and mortality especially in children. This audit describes the outcome of pediatric sepsis in the University Hospital of the West Indies, Kingston, Jamaica using data derived from the administrative hospital records from 2010 to 2014.

Methods:

The University Hospital of the West Indies Jamaica is a tertiary centre that accepts referral for pediatric malignancies, dialysis across the island and has a special neonatal care unit that manages newborns. Data were abstracted from hospital records of a retrospectively cohort of children identified with sepsis, septicemia and neonatal sepsis using the international classification of diseases 10th Revision (ICD code 10). Analysis of the hospital records of children 0-16 years at the time of admission to hospital. Descriptive hospital statistics are reported.

Results:

A total of 7211 children, between 0 and 16 years of age with a male female ratio of 1.27:1 were admitted between January 2010 and December 2014. There were 801 children hospitalized for pediatric sepsis with a male female ratio of 1.27 to 1. The median length of hospitalization was 10 days (range 0 to 366 days, IQR was between 7 days and 19 days). The rate of sepsis was low in older children and adolescents.  Among children with sepsis, neonates were 79% (n=691). Preterm infants represent 37% (n=250) of septic neonates. The mortality rate for sepsis amongst neonates in this study was 11 % (n=70). The mortality rate among preterm was 20 % (n=46/250) and 6.3% (26/434) in term neonates with sepsis. The crude mortality rate in children with sepsis above 2 years was 38% (12/47). The annual crude mortality rate for pediatric sepsis ranged from 9% to 11% with no significant difference across the years. The crude mortality rate for sepsis was 12 per 1000 pediatric hospitalizations.

Conclusion:

The mortality rate for pediatric sepsis is high and is comparable to reports of sepsis mortality from the United States in 2003.Sepsis in the neonatal age group was associated with significant co-morbid factors such as preterm delivery. This audit provides a baseline for targeted reduction in sepsis mortality by 1/3 in 2020 according to the global sepsis campaign.

Oluwayomi Olugbuyi, MBBS DM, Child and Adolescent Health, University of the West Indies, Kingston, Jamaica, Celia Christie-Samuels, MD, MPH, Department of Obstetrics, Gynaecology, and Paediatrics, University of the West Indies, Kingston, Jamaica, Kathryn Swaby, MBBS, Child and Adolescent Health, University of the west indies, Kingston, Jamaica and Patrick Robert, MBBS DM, Surgery, University of the west indies, Kingston, Jamaica

Disclosures:

O. Olugbuyi, None

C. Christie-Samuels, None

K. Swaby, None

P. Robert, None

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