Methods: GC and CT PID cases reported by the Calgary and Edmonton STI Clinics from January 1, 2004 to September 30, 2014 were reviewed. Clinical criteria for PID diagnosis were cervical motion tenderness +/- adnexal tenderness. Improved disposition was defined as no worsening of symptoms at the follow-up visit. Treatment failures were defined as those with persistent symptoms requiring additional treatment and no sexual contact between the start of treatment and follow-up visit. Descriptive analysis was completed using IBM SPSS Statistics version 19.0 (IBM, Armonk, NY, USA). Ethics approval was obtained from the University of Alberta’s Health Research Ethics Board.
Results: One hundred PID cases were reviewed. The median age of cases was 20 years (IQR: 18-26). Most cases were Caucasian (n=56) and 6 cases were pregnant. The majority of cases (n=81) were diagnosed with CT alone, 12 cases with GC alone and 7 cases were co-infected with GC and CT. Co-infections with bacterial vaginosis (n=32) and trichomoniasis (n=3) also occurred. Most cases (n=73) were treated with ceftriaxone 250 mg IM and doxycycline 100 mg bid for 14 days +/- metronidazole 500 mg bid for 14 days, 17 cases were treated with ofloxacin 400 mg bid for 14 days +/- metronidazole, and the remaining cases (n=10) were treated with other drug regimens. Over one-half of (n=58) cases returned for follow-up, of which 10 cases (17.2%) had not improved. Six of the cases that did not improve were due to re-exposure (n=4), non-adherence (n=1), and intolerance of medications (n=1); one case was lost to follow up. The remaining 3 cases were treatment failures; all were treated with ofloxacin, resulting in a 30% treatment failure rate for ofloxacin treated cases who returned for follow-up (3/10 cases).
Conclusion: The majority of PID cases were treated according to Alberta STI guidelines. All cases treated with ceftriaxone and doxycycline +/- metronidazole responded to treatment while all treatment failures were treated initially with ofloxacin.
J. Brandley, None
P. Smyczek, None
P. Parker, None
R. Read, None
A. Singh, None
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