1577. Urinary Tract Infection (UTI) and Its Association with Preterm Labor: Findings from the Mississippi Pregnancy Risk Assessment Monitoring System (PRAMS), 2009-2011
Session: Poster Abstract Session: Clinical Infectious Diseases: UTIs
Saturday, October 10, 2015
Room: Poster Hall
Background:

UTI is the most common infection during pregnancy in the United States that may lead to maternal morbidity and adverse birth outcomes. Despite the evident relationship between UTI and maternal and neonatal morbidity, little is known about the prevalence of UTI during pregnancy and its association with preterm labor among pregnant women in Mississippi. This study aimed to estimate prevalence of UTI and explore its association with preterm labor among pregnant women in Mississippi. 

Methods:

The 2009-2011 Mississippi PRAMS data (n=3,836) were analyzed. PRAMS is an on-going national surveillance system designed to identify and monitor maternal behaviors and experiences before, during and after pregnancy among women delivering a live birth. Data were weighted to reflect the PRAMS complex survey design. The dependent variable of the study was preterm labor. UTI was main independent variable and covariates included blood pressure, gestational diabetes, obesity, smoking, drinking and socio-demographic variables (age, race, education and income). Descriptive statistics, Chi-square, binary and multiple regressions were done using SAS 9.3 PROC SURVEY (SAS Institute, Cary, NC, USA). 

Results:

Overall, prevalence of UTI among pregnant women in Mississippi was 60% (95% CI: 57.0-62.9). Among these women, 38.4% were 20-24 years old, 57% were White, 36.6% had less than $10,000 income and 54.3% had high school education. With multiple logistic regression, we found that women who had UTI during their pregnancy were approximately 2 times more likely to have a preterm labor (OR=1.8, 95% CI=1.3-2.4) after adjusting for covariates. Also, no interaction between independent variable and covariates was observed.

Conclusion:

The findings demonstrate high prevalence of UTI during pregnancy in Mississippi. In addition, having UTI during pregnancy is significantly associated with higher odds of preterm labor. Given that UTI is associated with poor pregnancy outcomes, early diagnosis followed by immediate therapy is essential during pregnancy to avoid adverse maternal and neonatal health outcomes.

Mina Qobadi, PhD, Health Data and Research, Mississippi State Department of Health, Jackson, MS and Ali Dehghanifirouzabadi, MD, STD/HIV, Mississippi State Department of Health, Jackson, MS

Disclosures:

M. Qobadi, None

A. Dehghanifirouzabadi, None

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