Methods: Stratified probability proportional to size sampling methodology. A total of 824 pregnant women from 60 clusters were enrolled. After obtaining informed consent, participants’ socio-demographic and fertility characteristics were collected by interview questionnaire. All the tested women had no history of rubella vaccination. Anti-rubella IgM and IgG titers were studied from blood samples by micro ELISA.
Results: Of the 803 samples tested for rubella antibodies, 753 cases (93.8%) had anti-rubella IgG positivity, indicating a past infection. Five of the pregnant women (0.6%) had both anti-rubella IgM and IgG positive results, suggesting a recent infection. The remaining 45 women (5.6%) were seronegative for both antibodies. Seroprevalence was not associated with age or urban/rural residency. All the five anti-rubella IgM positive women were in the second trimester of pregnancy.
Conclusion: As 5.6% of pregnant women were susceptible to rubella during pregnancy, and five of them had already had a recent infection, immunization efforts should be directed at earlier ages like infancy or adolescent period.
M. Ozen, None
M. Tekerekoglu, None
M. Genc, None