1588. Risk Factors Associated with 30-day Readmission in Patients with Community Acquired Pneumonia
Session: Poster Abstract Session: Community Acquired Pneumonia
Saturday, October 10, 2015
Room: Poster Hall

Pneumonia is a severe health problem in the United States responsible for close to 1 million hospital admissions and nearly 140,000 re-admissions per year. Given the impact of high readmission rates to hospitals nationally, it is important to identify patients at highest risk of readmission.  The purpose of our study was to investigate in a large multicenter cohort over a several year period, the association of specific risk factors with 30-day readmission in patients presenting with community acquired pneumonia(CAP). 


This is a retrospective multicenter analysis of patients with pneumonia over an 11-year period from 4 large health care institutions. Participating centers included Henry Ford Health System, University of Maryland Medical System, Baylor Health Care System and Barnes Jewish Hospital. Patients were identified by diagnostic codes.  Specifically, CAP patients were identified as those who received ceftriaxone, azithromycin, or respiratory fluoroquinolones within 24 hours of hospitalization. A computer stores generated database was used to obtain demographic data including age, sex, cultured organism, Charlson comorbidity index, length of stay (LOS) and therapy.


There were 22,404 patients classified as CAP who did not expire during initial hospitalization. 13% were readmitted for any cause within 30 days. Those readmitted were found to have significantly longer hospital initial LOS (10.8 vs 7.7 days, p <0.001), higher Charlson co-morbidity index (4.2 vs 3.6, p<0.001), and older age (over 62 years p<0.001).  Organisms associated with higher readmission rates include MRSA and gram negatives (p<0.001). S. pneumoniae did not show a significant difference. Patients without sputum obtained and organism identification had lower readmission rates (p<0.001).


The results of our multicenter study suggest that CAP patients with more comorbid conditions have increased risk of 30-day readmission rates. Organism identification was helpful in patients to direct therapy. However, those patients without organisms identified had less readmissions suggesting appropriate coverage by current CAP regimens. Identifying high risk patients early on should prompt more aggressive discharge follow up, patient education, and culture screening to potentially reduce readmissions.

Yuan Xin, MPH1, Rebecca Bajoka, DO2, Ruchira Sengupta, MD1, Daniela Moreno, MPh3, Anthony D. Harris, MD, MPH, FIDSA, FSHEA4, Steven J. Lawrence, M.D., M.Sc.5, Andrew Masica, MD, MSCI6, Lois Lamerato, PhD7 and Marcus Zervos, MD, FIDSA8, (1)Henry Ford Hospital, Detroit, MI, (2)Henry Ford Hospital / Wayne State University, Detroit, MI, (3)Infectious Diseases, Henry Ford Hospital, Detroit, MI, (4)Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, (5)Washington University, St. Louis, MO, (6)Baylor Health Care System, Dallas, TX, (7)Henry Ford Health System, Detroit, MI, (8)Division of Infectious Diseases, Henry Ford Hospital, Detroit, MI


Y. Xin, pfizer: Investigator , Research support

R. Bajoka, pfuzer: Investigator , Research support

R. Sengupta, pfizer: Investigator , Research support

D. Moreno, pfizer: Investigator , Research support

A. D. Harris, pfizer: Investigator , Research support

S. J. Lawrence, Merck: Consultant , Consulting fee
pfizer: Investigator , Research support

A. Masica, pfizer: Investigator , Research support

L. Lamerato, pfizer: Investigator , Research support

M. Zervos, Pfizer: Principle investigator , Research grant to Henry Ford Hospital
Cerexa: Principle investigator , Research grant to Henry Ford Hospital
Tetraphase: Principle investigator , Research grant to Henry Ford Hospital

Findings in the abstracts are embargoed until 12:01 a.m. PDT, Wednesday Oct. 7th with the exception of research findings presented at the IDWeek press conferences.