Surgical site infections (SSI) are the most common health-care-associated infections in developing countries. Cancer patients are particularly at risk. However there are few reports that fully describe this entity. Our goal is to describe the microbiological spectrum and resistance patterns of the most common bacteria associated with of SSI in cancer patients at a tertiary care center.
We conducted a retrospective review of microbiologic data from January 2008 to December 2014. Samples from patients that did not meet the criteria for SSI according to CDC guidelines were excluded. Bacteria were identified using an automated microbiology system (BD Phoenix 100) and resistant isolates were confirmed using a disc diffusion method.
A total of 23,421 surgeries were performed at our Institution during the study period. We identified 1863 SSI, of which 60% were monomicrobial and 40% polymicrobial. Gram negative bacilli (GNB) were found in 56.5% of samples, with Escherichia coli as the most frequent microorganism (27.5%), followed by other GNB (17.7%) and Staphylococcus aureus (16.3%). Extended spectrum beta lactamase (ESBL) producing E. coli increased throughout the study period from 40% in 2008 to 77% in 2014. Fluoroquinolone resistance also increased in all members of the Enterobacteriaceae family.Methilcillin resistant S. aureus (MRSA) remained stable at 32% throughout the study period. Vancomycin resistant Enterococcus faecium was infrequent and never surpassed 13% of Enterococci isolates.
M. F. Golzarri,
M. Ostrosky, None
C. Velazquez-Acosta, None
P. Cornejo-Juarez, None
D. Vilar-Compte, None
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