Methods: We conducted a retrospective review of adult patients with GDS bacteremia who were hospitalized at Siriraj Hospital between 1 January 2009 to 30 June 2011. Clinical characteristics including predisposing factors and microbiological data were analyzed.
Results: One hundred and forty-seven episodes of bacteremia caused by GDS were included. Seventy-eight patients (58.2%) were male. Patients’ mean age was 63 years. Of 147 GDS isolates, 134 (91.2%) were identified as S. pasteurianus, 6 (4.1%) were S. gallolyticus, 2 (1.4%) were S. infantarius, 1 (0.7%) were S. lutetiensis and 4 isolates (2.7%) were unidentifiable. Cirrhosis was identified as underlying disease in 87 patients (59.2%). Eighty-three patients (56.5%) had primary bacteremia and 49 patients (33.3%) had secondary bacteremia from spontaneous bacterial peritonitis. Thirty patients (20.9%) underwent colonic evaluation and colonic polyps were the most common finding found in 8 patients. Colonic cancer was diagnosed in 5 patients with GDS bacteremia in which 4 of 5 patients were diagnosed previously and before the bacteremic episodes. Bacteremia due to S. pasteurianus was associated with patients who had cirrhosis (p = 0.041), whereas S. gallolyticus was more likely to be associated with non-cirrhotic patients (p = 0.031). Overall mortality of patients with GDS bacteremia was 22%.
Conclusion: S. pasteurianus was the most common species isolated in patients with GDS bacteremia and is associated with chronic liver disease.
A. Leelaporn, None