1532. Multicenter Study of Skin and Soft Tissue Infections Complicated in Hospitalized Patients 2009-2014 in Colombia
Session: Poster Abstract Session: Clinical Infectious Diseases: Soft Tissue Infections (ABSSSIs)
Saturday, October 10, 2015
Room: Poster Hall
Posters
  • Poster IPTB.jpg (1.2 MB)
  • Background:

    To create a national data base involving the description and analysis of the epidemiology, etiology, risk factors, clinical manifestations, treatment and outcomes of hospitalized patients with complicated skin and soft tissue infections (SSTIs) in tertiary centers around the country, in order to establish strategies that reduce the morbidity and mortality generated by these type of infections.

    Methods:

    We did a retrospective observational study from January 2009 to December 2014 of patients including age more than 18 year old with a diagnosis of SSTI, in the eleven tertiary centers around the country, that required hospitalization for at least 48 hours or during their hospital stay they developed the infection. We excluded patients with organ/space SSI, osteomyelitis and septic arthritis with concomitant affected skin. 

    Results:

    1000 patients with skin and soft tissue infections were collected. Half of the patients were men. 57.7% of the patients were from a low socioeconomic stratum, 37% (n: 370) did not have any comorbidity. The vast majority of patients acquired the infection in the community (77.1%), followed by 10.1% acquired in health care facilities. The type of infection was, in order of frequency, cellulitis with 50.6% (n: 506), abscess 32.8% (n: 328) and tenosynovitis 10.8% (n: 108). The most prevailing clinical manifestations were pain 83.7% (n: 837), edema 77.7% (n: 777) and erythema 70% (n: 700). The average treatment duration was 9 days. In patients with cultured samples (65.3%), we found that 37% were Staphylococcus aureus.  The 22% of cultures were negative. Of these isolations 68.7% were methicillin resistant, being the most prevailing one the community phenotype (75%). The 54% of the empirical treatment covered methicillin sensitive Staphylococcus aureusand the empirical treatment was changed in 44% of cases. We found a 2.9% of all-cause mortality. 

    Conclusion:

    We found that the majority of patients with SSTIs were acquired in the community and occurred in young people. These patients had a prolonged hospital stay that can be related to an inappropriate empiric treatment, covering only methicillin sensitive Staphylococcus aureus. In this study we found a high prevalence of methicillin resistant Staphylococcus aureus consequently, this microorganism must by covered in the empirical treatment of SSTIs in Colombia.

    Sandra Valderrama, MD1, Carlos Arturo Alvarez Moreno, Physician infectious diseases1, Sandra Gualtero, MD2, Johanna Osorio, MD3, Jose Rodriguez, MD4, Carlos Gomez Quintero, MD5, Ivan Tenorio, MD6, Gerson Arias, MD7, Alvaro Ruiz, MSc8, Sebastian Mackenzie, MD2, Alberto Zhong, MD2 and Maria Alejandra Caro, MD2, (1)Infectious Diseases, Hospital Universitario San Ignacio, Bogotá, Colombia, (2)Hospital Universitario San Ignacio, Bogota, Colombia, (3)Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia, (4)Hospital Rosario Pumarejo Lopez, Valledupar, Colombia, (5)Clinica de la Mujer, BOGOTA, Colombia, (6)Clinica San Juan de Dios, Cartagena, Colombia, (7)Hospital Santa Clara, Bogota, Colombia, (8)Pontificia Universidad Javeriana, Bogota, Colombia

    Disclosures:

    S. Valderrama, None

    C. A. Alvarez Moreno, None

    S. Gualtero, None

    J. Osorio, None

    J. Rodriguez, None

    C. Gomez Quintero, None

    I. Tenorio, None

    G. Arias, None

    A. Ruiz, None

    S. Mackenzie, None

    A. Zhong, None

    M. A. Caro, None

    Findings in the abstracts are embargoed until 12:01 a.m. PDT, Wednesday Oct. 7th with the exception of research findings presented at the IDWeek press conferences.