1207. Salmonella Infection in Older Adults: A Prospective Study of Incidence And Risk Factors
Session: Poster Abstract Session: Clinical Infectious Diseases: Enteric Infections
Friday, October 28, 2016
Room: Poster Hall
Posters
  • Salmonella.pdf (929.4 kB)
  • Background: Salmonella infection is a globally important cause of foodborne disease. We investigated the incidence and risk factors for notification and hospitalization due to Salmonella infection in older adults.

    Methods: We used the 45 and Up Study, a large-scale Australian prospective study of adults aged ≥45 years, with record linkage to multiple databases for the years 2006–2012 to estimate the incidence of notification and hospitalization for Salmonella infection and estimate hazard ratios (HRs) using Cox regression.

    Results: Over a total follow-up of 1,120,242 person-years, 333 adults were notified with Salmonella infection and 101 were hospitalized; the notification and hospitalization rates were 29.7 (95%CI: 26.9-33.3) and 9.0 (95%CI: 7.4-10.9) per 100,000 person-years, respectively. The risk of Salmonella infection notification did not differ by age, but risk of hospitalization increased with age. The risk of notification was higher for those living in outer regional or remote areas (aHR 2.05, 95%CI 1.35-3.10), those taking proton pump inhibitors (PPIs) (aHR 1.87, 95%CI 1.43-2.40), and those reporting chicken/poultry intake at least once per day (aHR 3.16, 95%CI 1.25-7.98).

    Conclusion: Elderly males had the highest risk of infection-related hospitalization. Chicken consumption remains a significant risk factor for Salmonella infection, highlighting the importance of reducing contamination of poultry and improving food safety advice for older people.

    Yingxi Chen, BM, MPH(Res)1, Kathryn Glass, PhD1, Bette Liu, PhD2 and Martyn Kirk, PhD1, (1)Research School of Population Health, Australian National University, Canberra, Australia, (2)University of New South Wales, Sydney, Australia

    Disclosures:

    Y. Chen, None

    K. Glass, None

    B. Liu, None

    M. Kirk, None

    Findings in the abstracts are embargoed until 12:01 a.m. CDT, Wednesday Oct. 26th with the exception of research findings presented at the IDWeek press conferences.