Methods: We used the 45 and Up Study, a large-scale Australian prospective study of adults aged ≥45 years, with record linkage to multiple databases for the years 2006–2012 to estimate the incidence of notification and hospitalization for Salmonella infection and estimate hazard ratios (HRs) using Cox regression.
Results: Over a total follow-up of 1,120,242 person-years, 333 adults were notified with Salmonella infection and 101 were hospitalized; the notification and hospitalization rates were 29.7 (95%CI: 26.9-33.3) and 9.0 (95%CI: 7.4-10.9) per 100,000 person-years, respectively. The risk of Salmonella infection notification did not differ by age, but risk of hospitalization increased with age. The risk of notification was higher for those living in outer regional or remote areas (aHR 2.05, 95%CI 1.35-3.10), those taking proton pump inhibitors (PPIs) (aHR 1.87, 95%CI 1.43-2.40), and those reporting chicken/poultry intake at least once per day (aHR 3.16, 95%CI 1.25-7.98).
Conclusion: Elderly males had the highest risk of infection-related hospitalization. Chicken consumption remains a significant risk factor for Salmonella infection, highlighting the importance of reducing contamination of poultry and improving food safety advice for older people.
B. Liu, None
M. Kirk, None