Methods: We administered a prospective survey to HIV+ AYAs between the ages of 13-24 from October 2013 to February 2016 to determine the prevalence of IDU, and evaluate the influence of IDU on care retention and viral suppression. Retention in care was defined as compliance with ≥90% of scheduled clinic visits in the 6 months prior to enrollment. Viral suppression was defined as a mean HIV-1 RNA viral load of <200 copies/ml in the same time period to account for viral blips. Logistic regression was used to evaluate IDU associations and identify other risk factors.
Results: 200 participants were enrolled, with a mean age of 21±2.4 years. Forty six percent of participants admitted to current IDU, with marijuana as the most commonly used drug. Univariate analysis showed lack of viral suppression in AYAs with any IDU (OR=2.03, 95% CI: 1.15-3.58) and marginally with high school education or less (OR=1.71, 95% CI: 0.94-3.12). In the multivariable model, lack of viral suppression maintained associations with any IDU (aOR=2.09, 95% CI: 1.12-3.89) and a high school education or less (aOR=2.18, 95% CI: 1.14-4.19). AYAs who were retained in HIV care were less likely to have poor viral control (aOR=0.22, 95% CI: 0.10-0.50), but IDU was not associated with retention in HIV care (aOR=1.32, 95% CI: 0.69-2.54). Sub-analyses found marijuana use was associated with a lack of viral suppression (aOR=2.19, 95% CI: 1.17-4.07).
Conclusion: High prevalence of IDU among HIV+ AYAs and its association with poor viral control demonstrates the need for interventions specifically designed for this population including strategies to decrease marijuana consumption.
J. Hood, None
L. Seaton, None
A. Camacho-Gonzalez, None