257. Prevalence of Respiratory Viruses, including Influenza, Among Nursing Home Residents and High-Touch Room Surfaces
Session: Poster Abstract Session: HAI: Environment and Device Cleaning
Thursday, October 27, 2016
Room: Poster Hall
Background: Nursing homes (NH) are a unique environment for the spread of respiratory viruses. Outbreaks due to Influenza A have been previously reported, but there are few data on viral etiologies in non-outbreak settings. The advent of rapid molecular multiplex methods now provide the ability to understand more about non-outbreak viral respiratory infections in NH residents and the potential of shedding to high-touch surfaces.

Methods: NH residents with acute onset respiratory symptoms were identified from three Southern California NHs from June-August 2015. Bilateral nares swabs were obtained and five high touch room surfaces were sampled: 1) table/bedrails, 2) call button/remote/phones, 3) light switches, 4) bathroom rail/handles, and 5) door/handles. All samples were processed utilizing the FilmArray Respiratory Panel (RP) (Biofire Diagnostics), an FDA-approved automated multiplex nested PCR system. The FilmArray instrument system tests for a standard panel of viruses (Influenza (A, A/H1, H3, and H1-2009), influenza B, RSV, parainfluenza virus 1-4, adenovirus, coronavirus (299E, HKU1, OC43, NL63), human metapneumovirus, and human rhinovirus/enterovirus).

Results: A total of 52 residents and 260 environmental surfaces underwent multiplex testing. Among these residents, 19% (10/52) had a detectable viral pathogen: parainfluenza-3 (n=4), rhinovirus/enterovirus (n=4), RSV (n=1), and influenza B (n=1). Environmental contamination was found in 20% (2/10) of total room surface swabs (bedrail n=1, door n=1). Viral species from environmental swabs were all concordant with positive patient results.

Conclusion: In a non-outbreak setting, we identified viral respiratory pathogens in one-fifth of NH residents during the summer. One-fifth of high touch room surfaces were contaminated with the same virus, suggesting some environmental contamination. Our findings confirm that viral infections are common with summer respiratory symptoms in NH residents and subsequent environmental contamination may facilitate further spread. Findings may have implications for care of NH residents with respiratory symptoms and environmental cleaning of their rooms.

John Diaz-Decaro, MS1, Bryn Launer, BA2, James a. Mckinnell, MD3, Raveena Singh, MA4, Tabitha Dutciuc, MPH4, Nicole Green, PhD, D(ABMM)1, Michael Bolaris, MD2, Susan S. Huang, MD, MPH, FIDSA, FSHEA5 and Loren Miller, MD, MPH6, (1)Los Angeles County Department of Public Health, Downey, CA, (2)Infectious Disease Clinical Outcomes Research Unit, Division of Infectious Disease, Los Angeles Biomedical Research Institute at Harbor–University of California Los Angeles Medical Center, Torrance, CA, (3)Division of Infectious Diseases, Los Angeles Biomedical Research Institute Harbor-UCLA Medical Center, Torrance, CA, (4)Division of Infectious Diseases and Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, CA, (5)Division of Infectious Diseases, Department of Medicine, University of California Irvine, Irvine, CA, (6)Infectious Disease Clinical Outcomes Research (ID-CORE), LA Biomed at Harbor-UCLA Medical Center, Torrance, CA

Disclosures:

J. Diaz-Decaro, None

B. Launer, None

J. A. Mckinnell, None

R. Singh, None

T. Dutciuc, None

N. Green, None

M. Bolaris, None

S. S. Huang, None

L. Miller, None

Findings in the abstracts are embargoed until 12:01 a.m. CDT, Wednesday Oct. 26th with the exception of research findings presented at the IDWeek press conferences.