991. Point Prevalence Survey of Antimicrobial Prescriptions at a Tertiary Hospital in Southern Ireland, 2015
Session: Poster Abstract Session: Antibiotic Stewardship: General Acute Care Implementation and Outcomes
Friday, October 28, 2016
Room: Poster Hall
  • 991 Point Prevalence Survey of Antimicrobial Prescriptions at a Tertiary Hospital in Southern Ireland, 2015.pdf (233.5 kB)

    Background: Point prevalence surveys (PPSs) are useful to obtain a detailed snapshot of antimicrobial prescribing patterns in a hospital setting. This provides a picture of antimicrobial usage and informs investigators of areas that need further interventions for improvement.  It can also be used to assess local guideline compliance. Cork University Hospital is a tertiary referral hospital in the South of Ireland with a broad range of medical and surgical specialties.

    Methods: The study was conducted between 14th September and 10th October 2015 using a standardised protocol and data collection form. All inpatients in the hospital were included.  All drug charts were reviewed for current systemic antimicrobial prescriptions and data were subsequently analysed using Excel management software.

    Results: Two hundred and nineteen patients out of 505 patients were prescribed antimicrobials (43%) and a total of 344 antimicrobials were charted. The numbers of antimicrobials for patients in surgical, medical and intensive care wards were 35%, 56%, and 6% respectively. Piperacillin-tazobactam was the most commonly prescribed antimicrobial (21%), followed by amoxicillin-clavulanate (15%), vancomcyin (10%), metronidazole (7%), and flucloxacillin (6%). Pneumonia was the main indication for all prescriptions (28%), followed by skin & soft tissue infections (15 %,) and intra-abdominal infections (8%). Ninety four percent of patients who received surgical prophylaxis received <24 hours of antimicrobials.  Seventy percent were charted as intravenous. Of these, 14 prescriptions (6%) were assessed as inappropriate. Only 31% of prescriptions had a proposed duration specified and 94% had a correct dose prescribed. In total, 20% of prescriptions were assessed as inappropriate.

    Conclusion: Forty-three percent of inpatients were prescribed antimicrobials and 80% were deemed appropriate. The hospital compares well with national figures. Piperacillin/tazobactam was the most commonly prescribed agent. Ongoing antimicrobial stewardship by the antimicrobial stewardship team and clinical pharmacists is important to ensure high levels of appropriate antimicrobial prescribing at individual patient level to improve patient outcomes.


    Zakariya Al Balushi, MD, Infectious Diseases, Cork Univesity Hospital, Cork, Ireland, Mala Shah, BPharm, MSc Clinical Pharmacy Practice, Pharmacy, Cork University Hospital, Cork, Ireland, Diana Hogan-Murphy, BA, H.Dip (Computer Science), Masters in IT, B.Sc in Pharmacy, M.Sc in Clinical Pharmacy, University Hospital Galway, Galway, Ireland and Arthur Jackson, MD, Infectious Diseases, Cork University Hospital, Cork, Ireland; Infectious Diseases, Mercey University Hospital, Cork, Ireland


    Z. Al Balushi, None

    M. Shah, None

    D. Hogan-Murphy, None

    A. Jackson, None

    Findings in the abstracts are embargoed until 12:01 a.m. CDT, Wednesday Oct. 26th with the exception of research findings presented at the IDWeek press conferences.