1187. Central neurological complications in tuberculous meningitis in HIV-negative adults
Session: Poster Abstract Session: Clinical Infectious Diseases: CNS Infection
Friday, October 28, 2016
Room: Poster Hall
Background:The aim was to study the epidemiological and evolutionary aspects, clinical, paraclinical, therapeutic neurological complications of tuberculous meningitis.

Methods: A Retrospective study was conducted over 11 years in the department of infectious diseases including all HIV-negative patients with tuberculous meningitis confirmed

Results:

We collected 68 patients. The average age was 35 years with a female predominance. The diagnosis was confirmed by isolation of Mycobacterium Tuberculosis in CSF (64.70 %) , in other locations that neuromeningitis ( 44.11 %). Hydrocephalus was the most common abnormality (50 %), followed tuberculomas (10.2%) and arachnoiditis (8.8%). Meningoencephalitis was found in 7.35% of cases, spondylodiscitis (7.35 %), the epidural (5.88 %) and brain abscess (5.88 %). Myelitis and syringomyelia were objectified in 1.4 % of cases each. All patients were treated with quadruple tuberculosis. The corticosteroid therapy was prescribed in 88.2 % of cases and intrathecal in 17.6 % of cases. Surgical treatment was performed in 22% of patients. The evolution was marked by the recovery in 89.7 % of cases, persistent sequelae (27.9%), relapse (2 cases), and death (10.2%).

Conclusion: Our study underlines the seriousness of the neuromeningitis location of tuberculosis

Latifa Badaoui, doctor, Infectious Diseases, Infectious diseases unit, Ibn Rochd University Hospital, Casablanca, Morocco and Kamal Marhoum El Filali, Professor and Department Head, Infectious diseases unit, Ibn Rochd University Hospital, Casablanca, Morocco

Disclosures:

L. Badaoui, None

K. Marhoum El Filali, None

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