Methods: A Retrospective study was conducted over 11 years in the department of infectious diseases including all HIV-negative patients with tuberculous meningitis confirmed
We collected 68 patients. The average age was 35 years with a female predominance. The diagnosis was confirmed by isolation of Mycobacterium Tuberculosis in CSF (64.70 %) , in other locations that neuromeningitis ( 44.11 %). Hydrocephalus was the most common abnormality (50 %), followed tuberculomas (10.2%) and arachnoiditis (8.8%). Meningoencephalitis was found in 7.35% of cases, spondylodiscitis (7.35 %), the epidural (5.88 %) and brain abscess (5.88 %). Myelitis and syringomyelia were objectified in 1.4 % of cases each. All patients were treated with quadruple tuberculosis. The corticosteroid therapy was prescribed in 88.2 % of cases and intrathecal in 17.6 % of cases. Surgical treatment was performed in 22% of patients. The evolution was marked by the recovery in 89.7 % of cases, persistent sequelae (27.9%), relapse (2 cases), and death (10.2%).
Conclusion: Our study underlines the seriousness of the neuromeningitis location of tuberculosis