1432. Trends in Early and Late Onset Group B Streptococcus in New York State, 2000 -2014
Session: Poster Abstract Session: Public Health
Friday, October 28, 2016
Room: Poster Hall
Posters
  • ID Week 2016 GBS Poster_FINAL.pdf (362.1 kB)
  • Background: Group B Streptococcus (GBS) is a leading cause of neonatal morbidity and mortality in the US. In infants, GBS is classified as either early onset (EO) (<7days of age) or late onset (LO) (7 – 89 days of age).  The Centers for Disease Control and Prevention (CDC) estimated that in the US in 2014, the EO GBS incidence rate was 0.24 cases per 1,000 live births and the LO GBS incidence rate was 0.27 per 1,000 live births.

    Methods:
    Through the Emerging Infections Program collaboration between the CDC and ten state health departments and academic partners, New York State’s (NYS) Active Bacterial Core Surveillance (ABCs) has conducted active population-based surveillance for GBS since 2000 in 15 counties in the Albany and Rochester regions (pop. 2.1 million).  Standardized case report forms are completed for all EO and LO GBS cases through medical record reviews.  EO and LO cases identified between 2000 and 2014 were analyzed. Incidence rates per 1,000 live births were calculated, and stratified by race.

    Results:
    There were 211 cases of EO (n=99) and LO (n=112) GBS in ABCs counties between 2000 and 2014. Rates fluctuated between 0.40 EO cases and 0.36 LO cases per 1,000 live births in 2000, and 0.35 EO and 0.31 LO cases per 1,000 live births in 2014. As shown in figure 1, incidence rates among black infants were substantially higher than white infants for both EO and LO.  Compared to EO cases, LO cases were more likely to be preterm (<37weeks) births, and/or low birthweight in both black and white infants, shown in figure 2. After adjusting for gestational age, incidence rates among black infants remained higher than rates among white infants.

    Conclusion:
    Slight improvements in the incidence in EO GBS seen following the revised screening guidelines in 2002 have diminished over time. Although the low number of cases of EO and LO GBS cases makes it difficult to assess true trends, the disparity in incidence by race has not diminished even after controlling for gestational age for LO cases. Further research is needed to identify risk factors that contribute to the disparity in outcome between black and white infants. 


    Figure 1



    Figure 2




    Jemma Rowlands, MPH, Rachel Wester, MPH, RN, Eva Pradhan, MPH, MHA, Priscela Perez, MPH and Shelley M. Zansky, PhD, New York State Department of Health, Albany, NY

    Disclosures:

    J. Rowlands, None

    R. Wester, None

    E. Pradhan, None

    P. Perez, None

    S. M. Zansky, None

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