Methods: From January 2015 to March 2016, all patients presenting to the Rhode Island STD Clinic who tested positive for N. gonorrhoeae by nucleic acid amplification testing were attempted to be cultured. Swabs were obtained, streaked onto Modified Thayer Martin Media (MTMM), and incubated at 36oC in a 5% CO2 atmosphere for 24 hours. Suspected N. gonorrhoeae isolates were plated onto chocolate agar and confirmed by matrix-assisted laser desorption/ionization (MALDI). Susceptibility testing was performed using the Etest (BioMerieux). Resistant/nonsusceptible was defined as the following: ceftriaxone (>0.25μg/mL), ciprofloxacin (
Results: A total of 149 patients tested positive for N. gonorrhoeae; of these, 58% (86/149) were swabbed. Of those swabbed, 76% (65/86) grew on MTMM plates and 63% (54/86) were confirmed by MALDI. Of those confirmed to be N. gonorrhoeae, 80% (43/54) were successfully tested for resistance. The average age was 30.4 years; 100% were male; 58% were White, 21% African American, and 19% Hispanic/Latino. Seventy-two percent were MSM; 40% of patients reported
Conclusion: Antimicrobial resistance to ciprofloxacin and doxycycline and to a lesser degree azithromycin occurred among N. gonorrhoeae isolated from a largely MSM population at the only STD Clinic in Rhode Island. Close monitoring and aggressive treatment of N. gonorrhoeae is warranted. No specific demographics or behaviors associated with resistance were identified.
M. Montgomery, None
A. Robinette, None
K. C. Chapin, None
J. Lonks, None
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