1422. Epidemiology of Lyme disease in Hispanics admitted to a tertiary medical center in Long Island
Session: Poster Abstract Session: Public Health
Friday, October 28, 2016
Room: Poster Hall
Posters
  • IDSA_Poster SBU Lyme.pdf (660.4 kB)
  • Background: Lyme disease (LD) is the most commonly reported vector-borne illness in the U.S., with an estimate of 300,000 people diagnosed with LD every year. A recent study from the CDC showed that Hispanics were more likely than non-Hispanics to have signs of disseminated infection and onset during fall months.We aim to describe the clinical presentation and epidemiological characteristics of LD in Hispanics (H) versus non-Hispanics (NH) who presented to Stony Brook University Hospital (SBUH) during the years of 2010-2015

    Methods: A retrospective chart review was performed in all patients with ICD-9 or ICD-10 diagnostic codes for LD from January 2010 to December 2015. Confirmed cases were defined by a clinical scenario compatible with LD (erythema migrans, arthritis, central nervous system (CNS) involvement, carditis) and serological confirmation by western blot according to CDC criteria. CNS involvement was defined as abnormal CSF fluid analysis consistent with meningitis. Persons self-identified as being of Hispanic ethnicity were included in the group H

    Results: Out of 767 cases coded as LD, 232 met inclusion criteria for this study [H: n=50 (31 men, 19 women) vs NH: n=182 (94 men, 88 women)] (p=0.2). The median age was 50 years (interquartile range (IQR): range: 29-63) and 52 years (IQR: 26-35) for H and NH, respectively (p=0.7). Erythema migrans was the most common presentation of LD in both groups, (H:42%, NH:43.9%; p=0.8), followed by arthritis (H:11.1%, NH:13.2%; p=0.5), peripheral neuropathy including Bell's palsy (H:10%, NH:20.3%; p=0.09), CNS involvement (H:6%, NH:9.9%; p=0.4) and carditis (H:4%, NH:3.3%; p=0.8). The H group was more frequently than the NH group to have disease onset during fall months (OR=2.01, 95%CI:0.95-4.28, p=0.06), whereas the H group was significantly less likely than NH to have disease onset during winter months (OR=0.2, 95%CI:0.05-0.88; p=0.03). Most patients were diagnosed with LD in the summer (H:56%, NH:55.5%;p=0.9) and in the spring (H:14%, NH:12.6%;p=0.8)

    Conclusion: Hispanics diagnosed with LD at this tertiary medical center presented with similar syndromes from LD than NH but the disease onset is more frequent during fall months than NH, in agreement with the recent CDC study. Additional studies are needed to clarify the underlying factors related to this epidemiological difference

    Yasin Abul, MD1, Robert Chow, MD1, Amy Spallone, MD2, Benjamin Luft, MD, FIDSA1 and Luis a. Marcos, MD, MPH1, (1)Infectious Diseases, Stony Brook University Hospital, Stony Brook, NY, (2)Internal Medicine, Stony Brook University Hospital, Stony Brook, NY

    Disclosures:

    Y. Abul, None

    R. Chow, None

    A. Spallone, None

    B. Luft, None

    L. A. Marcos, None

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