490. Clinical outcomes in Human Immunodeficiency Virus (HIV) positive individuals using an on-site outpatient pharmacy compared to off-site pharmacy options.
Session: Poster Abstract Session: HIV Care Continuum
Thursday, October 27, 2016
Room: Poster Hall
Background: Current literature is conflicting regarding the impact of pharmacy location on outcomes in HIV-infected individuals. The objective of this study is to evaluate viral load (VL) suppression in HIV-infected individuals receiving their prescriptions from an on-site pharmacy (ON-Rx) versus an off-site pharmacy (OFF-Rx).

Methods: This retrospective cohort study identified eligible patients from 2014-2015. The UTMC Ryan White Clinic has an in-clinic outpatient pharmacy (ON-Rx) serving clinic patients. The primary endpoint was achievement of VL < 40 copies/mL at the final VL measurement during 2015. Secondary endpoints included utilization of healthcare services and retention in care.

Results: 527 and 148 patients utilized an OFF-Rx or ON-Rx for their prescription medications, receptively. Differences in baseline characteristics were observed for median age (ON-Rx 50 years vs. OFF-Rx 46 years), income bracket, and medical insurance between the treatment groups (all p < 0.001). Patients using the ON-Rx were more likely to have VL suppression, maintain 2 clinic visits, and obtain 2 VL labs and 2 CD4 tests (figure 1). There was no difference in the rate of sexually transmitted infection screening (syphilis 96.6% vs 95.4%, gonorrhea 69.6% vs. 67.9%, chlamydia 69.6% vs. 68.1%; all p > 0.05), cervical cancer screening (41.7% vs 50.4%, p = .357), or utilization of other healthcare services (table 1) for the ON-Rx versus OFF-Rx groups, respectively.

Conclusion: Patients utilizing an ON-Rx had increased rates of VL suppression and retention in care, which are key components in the HIV Care Cascade.

Brian Lauer, Pharm D1, Joan Duggan, MD, FIDSA, FACP2, Eric Sahloff, PharmD, AAHIVP3, Lindsey Eitniear, PharmD1 and Rose Jung, PharmD3, (1)University of Toledo, Toledo, OH, (2)Department of Medicine, Division of Infectious Diseases, University of Toledo College of Medicine, Toledo, OH, (3)Pharmacy Practice, University of Toledo, Toledo, OH

Disclosures:

B. Lauer, None

J. Duggan, None

E. Sahloff, None

L. Eitniear, None

R. Jung, None

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