Methods: We obtained a total of 5,021 urine specimens during single patient visits to the OCHD between August 1, 2016 and January 31, 2017. Of these, 2,323 were from female subjects and 2,698 were from male subjects. Urine samples were tested for M. genitalium (using a research-use-only TMA assay) as well as C. trachomatis, N. gonorrhea, and T. vaginalis (using FDA approved PCR assays). Each patient also had VDRL titers drawn for syphilis testing.
Results: M. genitalium was the most frequent organism recovered in women with a prevalence of 11.11%, followed by C. trachomatis (7.40%), T. vaginalis (4.43%), N. gonorrhea (2.02%) and syphilis (0.65%). In men, M. genitalium was equally prevalent (12.31%) as C. trachomatis (10.67%), followed by N. gonorrhea (4.86%), T. vaginalis (3.48%) and syphilis (1.93%). All organisms, with the exception of syphilis, were more prevalent in African American men as compared to Caucasian men. No difference in prevalence was seen in women irrespective of race and there was no difference based on sexual orientation.
Conclusion: Our analysis showed that Mycoplasma genitalium is highly prevalent in our study population. This is of particular public health concern as this organism can result in a significant disease burden if left untreated. Azithromycin is the first-line agent against M. genitalium but can result in treatment failure in 13-32% of cases according to recent studies. For this reason, we advocate for the need to test for M. genitalium routinely in symptomatic patients at risk for sexually transmitted diseases.
P. Chittick, None
A. Gencay, None
B. Weberman, None
P. Hackert, None