Background: Novel disinfection tools have been used to supplement standard hospital cleaning protocols. This study was conducted to determine if the addition of Pulsed Xenon Ultraviolet disinfection (PX-UV) increased the effectiveness of manual cleaning with four different environmental cleaning and disinfecting agents and how their performance compared to the industry standard of sodium hypochlorite 10%.
Methods: Research staff collected 600 pre-clean, post-clean, and post-clean + PX-UV environmental samples of aerobic bacterial colonies (ABC) and MRSA from five high touch surfaces (bedrail, call button, toilet seat, bathroom grab rail, tray table). The PX-UV device was used three times - one five minute cycle on each side of the patient bed and one five minute cycle in the restroom.
Results: Wilcoxon signed-rank tests showed post-clean ABC counts were significantly different from post-clean + PX-UV clean counts for soap and water (p<0.001), quaternary ammonium compound (p<0.001), and hydrogen peroxide (p<0.001), but not for sodium hypochlorite 10% (p=0.78). A negative binomial mixed regression model showed that post-clean + PX-UV ABC counts for Soap and water were 8.6 times higher than post-clean ABC counts for sodium hypochlorite 10% solution, holding all other factors constant, p=0.001. Post-clean ABC counts for QAC + UV were 6 times higher than post-clean ABC counts for sodium hypochlorite 10% solution, holding all other factors constant, p=0.004. A Kruskal-Wallis test indicated there was no statistically significant difference in MRSA counts between cleaning chemicals at post-clean (p=0.1563) or post-clean + UV (p=0.337), indicating that the cleaning chemicals performed equally well at each stage. UV further statistically significantly lowered MRSA counts beyond the post-clean level only for the quaternary ammonium compound group (p=0.0073).
Conclusion: The addition of PX-UV significantly improves disinfection for soap and water, hydrogen peroxide, and quaternary ammonium compound, but not for sodium hypochlorite 10%. This improvement does not bring microbial levels to those seen when using sodium hypochlorite 10% alone.
F. Villamaria, None
M. Williams, None
L. Copeland, None
J. Zeber, None