765. Tuberculosis and Diabetes Mellitus among Prison Inmates in Peru: Results of a National Survey, 2016
Session: Poster Abstract Session: Tuberculosis and Other Mycobacterial Infections
Thursday, October 4, 2018
Room: S Poster Hall
Posters
  • poster_idweek_final.pdf (31.1 kB)
  • Background:

    Diabetes mellitus (DM) increases the risk of tuberculosis disease (TB) and is associated with poor TB treatment outcomes in the general population. We examined the relationship between TB and DM in prison inmates in Peru.

    Methods:

    We analyzed data from a cross-sectional, national survey of adult prison inmates in Peru conducted in 2016. The survey collected sociodemographic and medical information via standardized interview. Medical conditions were defined by self-report. We used multivariate logistic models for adjusted analyses of the relationship between TB and DM.

    Results:

    Of 75,971 inmates, 3,104 (4.3%) reported a history of TB diagnosis. Table 1 shows the characteristics of the TB and non-TB groups. The prevalence of DM was higher in the TB group compared to the non-TB group (4.2% vs. 2.4%; p<0.001). In multivariate analysis, DM was associated with twice the odds of having had a diagnosis of TB (adjusted OR=2.2; 95%CI: 1.8-2.7). Male sex, Spanish language, no college/university education, reimprisonment, hypertension and HIV infection were also associated with increased odds of prevalent TB (Figure 1).

    Conclusion:

    There was a high prevalence of TB among prison inmates in Peru. DM was associated with an increased likelihood of prevalent TB. Our results are consistent with findings in non-institutionalized populations and underscore the need to implement aggressive screening and treatment interventions for both TB and DM in prison settings.    

    Table 1. Characteristics of TB and non-TB groups in Peruvian prisons

    Variables

    TB group

    N=3,104

    Non-TB group

    N=72,331

    p-value

    Age in years, mean ± SD

    35.1 ± 10.4

    36.1 ± 11.5

    <0.001

    Male sex, n (%)

    3,053 (98.3)

    68,516 (93.8)

    <0.001

    College/University education, n (%)

    8,996 (6.6)

    201 (12.7)

    <0.001

    Spanish language, n (%)

    2,893 (93.2)

    64,295 (88.2)

    <0.001

    Reimprisonment, n (%)

    723 (27.0)

    9,110 (16.2)

    <0.001

    Hypertension, n (%)

    175 (4.7)

    3,399 (5.6)

    0.011

    Diabetes mellitus, n (%)

    131 (4.2)

    1,766 (2.4)

    <0.001

    HIV infection, n (%)

    65 (2.1)

    251 (0.3)

    <0.001

    Daniel Rojas-Bolivar, MD1, Zheng Zhu, PhD2, Yamilee Hurtado, PhD3, Milagros Zavaleta, MSc1, Jorge Sanchez, MD, MPH1,4, Roman Jandarov, PhD2, Jorge Alarcon, PhD1 and Moises Huaman, MD, MSc1,5, (1)Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales, Callao, Peru, (2)Division of Biostatistics and Bioinformatics, Department of Environmental Health, University of Cincinnati, Cincinnati, OH, (3)Boca Raton. Clinical Research Global Peru, Lima, Peru, (4)Asociación Civil Impacta Salud y Educación, Lima, Peru, (5)Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH

    Disclosures:

    D. Rojas-Bolivar, None

    Z. Zhu, None

    Y. Hurtado, None

    M. Zavaleta, None

    J. Sanchez, None

    R. Jandarov, None

    J. Alarcon, None

    M. Huaman, None

    Findings in the abstracts are embargoed until 12:01 a.m. PDT, Wednesday Oct. 3rd with the exception of research findings presented at the IDWeek press conferences.