754. Prevalence of latent tuberculosis infection among health care workers at a tertiary care university hospital
Session: Poster Abstract Session: Tuberculosis and Other Mycobacterial Infections
Thursday, October 4, 2018
Room: S Poster Hall
  • Poster_IDweek_2018_TB_CHOO.pdf (150.3 kB)
  • Background: We investigated the prevalence of latent tuberculosis infection (LTBI) among health care workers (HCWs) and analyzed its risk factors in a tertiary care university hospital in South Korea in a population with intermediate tuberculosis (TB) burden.

    Methods: A standard questionnaire regarding the baseline demographics and risk factors for LTBI was given to each participant. QuantiFERON-TB GOLD In-Tube (QFT-GIT) assay and chest radiography were performed to investigate the rate of LTBI.

    Results: A total of 1,429 participants, 213 (14.9%) doctors and 988 (69.1%) nurses and 228 (16.0%) others were enrolled. The mean age of the subjects was 33.0 years old, and 1,175 (82.2%) were female. Of the participants, 94.5% had received BCG vaccine. QFT-GIT assays were positive for 156 subjects (10.9%). Of the 213 doctors, 28 (13.1%) were positive by QFT-GIT, and among the 988 nurses, 94 (9.5%) had positive QFT-GIT results. Experience of working in hospital was significantly associated with positive LTBI test results by QFT-GIT assay. Gender and duration of employment as a HCW were significantly associated with having a positive QFT-GIT result in univariate analyses. In multivariate analyses, duration of employment as a HCW (>15 years) (odds ratio, 1.98; 95% confidence interval, 1.14-3.43) was independently associated with increased risk of a positive QFT-GIT result.


    A high prevalence of LTBI was found among our HCWs. Considering the association between the experience of working in hospital and high risk of LTBI. The risk for tuberculosis infection among HCWs was higher than general population, which suggests that stricter preventive strategies against nosocomial tuberculosis infection should be implemented.

    Eun Ju Choo, MD, Division of Infectious Diseases, Soonchunhyang University Bucheon Hospital, Bucheon, Korea, Republic of (South) and Se Yoon Park, Dr, Soonchunhyang University Hospital, Seoul, Korea, Republic of (South)


    E. J. Choo, None

    S. Y. Park, None

    Findings in the abstracts are embargoed until 12:01 a.m. PDT, Wednesday Oct. 3rd with the exception of research findings presented at the IDWeek press conferences.