1330. Diagnosis and Management of NTM Lung Disease: Effect of Online Educational Interventions on Infectious Disease Specialist Knowledge
Session: Poster Abstract Session: Medical Education
Friday, October 5, 2018
Room: S Poster Hall
  • diagnosis-and-management-of-ntm-lung-disease-effect-of-online-educational-interventions-on-infectious-disease.pdf (203.5 kB)
  • Background:

    Diagnosis and management of nontuberculous mycobacterial (NTM) lung disease is challenging for clinicians due to its rarity and the need for complicated, multidrug antibiotic regimens. The objective of this study was to determine whether online educational interventions can effectively address knowledge gaps among ID specialists regarding diagnosis and treatment of patients with NTM lung disease.


    Two educational interventions, consisting of a text-based activity with interactive questions, and a video-based discussion between two experts, were developed and made available online. Educational impact of each intervention was assessed using a 3-question repeated pairs pre-/post-assessment study design. Data from a sampling of learners were collected from 9/11/2017 through 1/17/2018. Statistical analyses included a paired (within-physician) 2-tailed t-test and McNemar’s χ2 statistic, with Cramer’s V to determine the overall effect of each intervention.    


    Overall, a total of 1273 ID specialist learners participated in the two activities from launch through 4/30/18. Analysis demonstrated a significant improvement (P <.05) in overall knowledge with considerable educational impact (V = .195 and .259). Improvements in specific areas included: (Figure). Despite gains in knowledge, additional gaps were also identified: (1) Regarding treatment of M. abscessus lung disease, 18% were unable to discern between guideline recommended therapies for M. abscessus and MAC complex NTM, and an additional 14% would treat with a less aggressive, non-curative regimen (n=211), and (2) regarding treatment of fibrocavitary MAC complex NTM; nearly one-third (31%) would treat a using a thrice-weekly regimen, despite an indication for a daily regimen (n=114).


    Participation in interactive text-based as well as video-based activities improved the ability of ID specialists to make evidence-based decisions in the care of NTM lung disease. The findings also uncovered educational needs that warrant further education in selecting appropriate therapeutic regimens particularly in cases where aggressive therapy is indicated.

    Edward Jackson, MD1, Piyali Chatterjee, BA1, Susan Smith, MN, PhD1, Karen Badal, MD, MPH1 and David E. Griffith, MD2, (1)Medscape Education, New York, NY, (2)University of Texas Health Sciences Center, Tyler, TX


    E. Jackson, Medscape: Employee , Salary .

    P. Chatterjee, Medscape: Employee , Salary .

    S. Smith, BioFire Diagnostics: Independent Medical Education , Educational grant .

    K. Badal, Medscape: Employee , Salary .

    D. E. Griffith, Aradigm Corporation: Advisor/consultant and Speaker's Bureau , Consulting fee and Speaker honorarium . Bayer Healthcare Pharmaceuticals: Advisor/consultant , Consulting fee . Grifols: Advisor/consultant and Speaker's Bureau , Consulting fee and Speaker honorarium . Insmed Incorporated: Advisor/consultant , Grant Investigator and Speaker's Bureau , Consulting fee , Grant recipient and Speaker honorarium .

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